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实施复杂胆石病的关键路径:将基于人群的数据转化为临床实践。

Implementation of a critical pathway for complicated gallstone disease: translation of population-based data into clinical practice.

机构信息

Department of Surgery, The University of Texas Medical Branch, Galveston, TX, USA.

出版信息

J Am Coll Surg. 2011 May;212(5):835-43. doi: 10.1016/j.jamcollsurg.2010.12.047. Epub 2011 Mar 12.

Abstract

BACKGROUND

Evidence-based guidelines recommend cholecystectomy during initial hospitalization for complicated gallstone disease. Previous studies and quality initiative data from our institution demonstrated that only 40% to 75% of patients underwent cholecystectomy on index admission.

STUDY DESIGN

In January 2009, we implemented a critical pathway to improve cholecystectomy rates for all patients emergently admitted for acute cholecystitis, mild gallstone pancreatitis, or common bile duct stones. We compared cholecystectomy rates during initial hospitalization, time to cholecystectomy, length of initial stay, and readmission rates in prepathway (January 2005 to February 2008) and postpathway patients (January 2009 to May 2010).

RESULTS

Demographic and clinical characteristics were similar between prepathway (n = 455) and postpathway patients (n = 112). Cholecystectomy rates during initial hospitalization increased from 48% to 78% after pathway implementation (p < 0.0001). There were no differences in operative mortality or operative complications between the 2 groups. For patients undergoing cholecystectomy on initial hospitalization, the mean length of stay decreased after pathway implementation (7.1 days to 4.5 days; p < 0.0001), primarily due to a decrease in the time from admission to cholecystectomy (4.1 days to 2.1 days; p < 0.0001). Thirty-three percent of prepathway and 10% of postpathway patients required readmission for gallstone-related problems or operative complications (p < 0.0001), and each readmission generated an average of $19,000 in additional charges.

CONCLUSIONS

Implementation of a multidisciplinary critical pathway improved cholecystectomy rates on initial hospitalization and lowered costs by shortening length of stay and markedly decreasing readmission rates for gallstone-related problems. Broader implementation of similar pathways offers the potential to translate evidence-based guidelines into clinical practice and minimize the cost of medical care.

摘要

背景

循证指南建议对复杂的胆石病患者在初次住院期间进行胆囊切除术。先前的研究和我们机构的质量倡议数据表明,只有 40%到 75%的患者在入院时接受了胆囊切除术。

研究设计

2009 年 1 月,我们实施了一个关键途径,以提高所有因急性胆囊炎、轻度胆石性胰腺炎或胆总管结石而紧急入院的患者的胆囊切除术率。我们比较了入院时初次住院、胆囊切除术时间、初始住院时间和再入院率的路径前(2005 年 1 月至 2008 年 2 月)和路径后患者(2009 年 1 月至 2010 年 5 月)。

结果

路径前组(n=455)和路径后组(n=112)的人口统计学和临床特征相似。路径实施后,初次住院期间的胆囊切除术率从 48%增加到 78%(p<0.0001)。两组在手术死亡率或手术并发症方面无差异。对于在初次住院期间行胆囊切除术的患者,路径实施后住院时间缩短(从 7.1 天缩短至 4.5 天;p<0.0001),主要是因为从入院到胆囊切除术的时间缩短(从 4.1 天缩短至 2.1 天;p<0.0001)。33%的路径前组和 10%的路径后组患者因胆石相关问题或手术并发症需要再次入院(p<0.0001),每次再入院平均产生 19000 美元的额外费用。

结论

多学科关键途径的实施提高了初次住院期间的胆囊切除术率,并通过缩短住院时间和显著降低胆石相关问题的再入院率降低了成本。更广泛地实施类似途径有可能将循证指南转化为临床实践,并最大限度地降低医疗保健成本。

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