Department of Surgery, The University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555-0541, USA.
J Gastrointest Surg. 2012 Nov;16(11):2011-25. doi: 10.1007/s11605-012-2024-1. Epub 2012 Sep 18.
Gallbladder disease is common and, if managed incorrectly, can lead to high rates of morbidity, mortality, and extraneous costs. The most common complications of gallstones include biliary colic, acute cholecystitis, common bile duct stones, and gallstone pancreatitis. Ultrasound is the initial imaging modality of choice. Additional diagnostic and therapeutic studies including computed tomography, magnetic resonance imaging, magnetic resonance cholangiopancreatography, endoscopic ultrasound, and endoscopic retrograde cholangiopancreatography are not routinely required but may play a role in specific situations.
Biliary colic and acute cholecystitis are best treated with early laparoscopic cholecystectomy. Patients with common bile duct stones should be managed with cholecystectomy, either after or concurrent with endoscopic or surgical relief of obstruction and clearance of stones from the bile duct. Mild gallstone pancreatitis should be treated with cholecystectomy during the initial hospitalization to prevent recurrence. Emerging techniques for cholecystectomy include single-incision laparoscopic surgery and natural orifice transluminal endoscopic surgery. Early results in highly selected patients demonstrate the safety of these techniques. The management of complications of the gallbladder should be timely and evidence-based, and choice of procedures, particularly for common bile duct stones, is largely influenced by facility and surgeon factors.
胆囊疾病很常见,如果处理不当,会导致高发病率、死亡率和额外费用。胆结石的最常见并发症包括胆绞痛、急性胆囊炎、胆总管结石和胆石性胰腺炎。超声是首选的初始影像学检查方法。其他诊断和治疗研究,包括计算机断层扫描、磁共振成像、磁共振胰胆管成像、内镜超声和内镜逆行胰胆管造影,并非常规要求,但在特定情况下可能发挥作用。
胆绞痛和急性胆囊炎最好通过早期腹腔镜胆囊切除术治疗。胆总管结石患者应采用胆囊切除术治疗,可在内镜或手术解除梗阻和清除胆管内结石后进行,也可与后者同时进行。轻度胆石性胰腺炎应在初次住院期间行胆囊切除术以预防复发。胆囊切除术的新兴技术包括单切口腹腔镜手术和经自然腔道内镜手术。在高度选择的患者中早期结果表明这些技术是安全的。胆囊并发症的处理应及时并基于证据,手术程序的选择,特别是针对胆总管结石,在很大程度上受医疗机构和外科医生因素的影响。