Department of Cardiology, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Medizinische Klinik mit Schwerpunkt Kardiologie, Augustenburger Platz 1, D-13553 Berlin, Germany.
Europace. 2011 Jun;13(6):796-802. doi: 10.1093/europace/eur046. Epub 2011 Mar 11.
The close topographic relationship between the left atrial posterior wall (LAPW) and the oesophagus creates a potential hazard of thermal lesions to the oesophagus during radiofrequency (RF) catheter ablation of atrial fibrillation (AF). The purpose of the study was to describe topographic relation of the oesophagus behind the left atrium in the ablation situation, and to evaluate the clinical outcome of subsequent modifications to the strategy using continuous real-time fluoroscopic visualization of the oesophageal course.
In 214 consecutive patients, a gastric tube (GT) was inserted before circumferential pulmonary vein isolation (CPVI) for the treatment of paroxysmal (n= 160) or persistent (n= 54) AF. In the real-time mapping situation at the LAPW, the tissue interface between catheter tip and oesophagus lumen measured only 2.9 ± 1.9 mm, and 2.5 ± 1.2 mm at the level of the upper and lower pulmonary vein (PV) ostia, respectively. Modifications of the intended antral CPVI approach due to an oesophageal course close to the left or right PV ostia (in 76.6% of patients) were associated with reduced success rate (sustained sinus rhythm) after one (54.9 vs. 72.0%, P = 0.03), or 1-3 ablation procedures (85.4 vs. 96.0%, P = 0.04) during a mean follow-up of 13 ± 10 months.
Continuous real-time fluoroscopic visualization using a GT emphasizes the very small distance of the catheter tip and oesophageal lumen that may be present in the real-ablation situation and may help to avoid RF lesion application in close proximity to the oesophagus. However, accordant modification of AF ablation strategy may reduce efficacy of the procedure.
左心房后壁(LAPW)与食管的紧密毗邻关系,在房颤(AF)的射频(RF)导管消融过程中,会增加食管热损伤的潜在风险。本研究旨在描述消融过程中左心房后壁后方食管的解剖关系,并评估通过连续实时透视可视化食管走行来改变策略后的临床结果。
在 214 例连续患者中,在进行环肺静脉隔离(CPVI)之前插入胃管(GT),以治疗阵发性(n=160)或持续性(n=54)AF。在实时 LAPW 标测时,导管尖端与食管管腔之间的组织界面仅为 2.9±1.9mm,在上、下肺静脉(PV)开口处分别为 2.5±1.2mm。由于食管紧邻左、右 PV 开口(76.6%的患者),对预期的窦房结 CPVI 方法进行修改,与单次消融(54.9% vs. 72.0%,P=0.03)或 1-3 次消融后(85.4% vs. 96.0%,P=0.04)的成功率降低相关,在平均 13±10 个月的随访中。
使用 GT 进行连续实时透视可视化强调了在真实消融情况下导管尖端和食管管腔之间可能存在的非常小的距离,这可能有助于避免 RF 损伤在紧邻食管的部位应用。然而,AF 消融策略的一致修改可能会降低手术的疗效。