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慢性阻塞性肺疾病评估测试(CAT):对肺康复的反应。一项多中心、前瞻性研究。

The COPD assessment test (CAT): response to pulmonary rehabilitation. A multicentre, prospective study.

机构信息

St George's Hospital NHS Trust, London, UK.

出版信息

Thorax. 2011 May;66(5):425-9. doi: 10.1136/thx.2010.156372. Epub 2011 Mar 12.

Abstract

BACKGROUND

The COPD (chronic obstructive pulmonary disease) assessment test (CAT) is a recently introduced, simple to use patient-completed quality of life instrument that contains eight questions covering the impact of symptoms in COPD. It is not known how the CAT score performs in the context of clinical pulmonary rehabilitation (PR) programmes or what the minimum clinically important difference is.

METHODS

The introduction of the CAT score as an outcome measure was prospectively studied by PR programmes across London. It was used alongside other measures including the St George's Respiratory Questionnaire, the Chronic Respiratory Disease Questionnaire, the Clinical COPD Questionnaire, the Hospital Anxiety and Depression score, the Medical Research Council (MRC) dyspnoea score and a range of different walking tests. Patients completed a 5-point anchor question used to assess overall response to PR from 'I feel much better' to 'I feel much worse'.

RESULTS

Data were available for 261 patients with COPD participating in seven programmes: mean (SD) age 69.0 (9.0) years, forced expiratory volume in 1 s (FEV(1)) 51.1 (18.7) % predicted, MRC score 3.2 (1.0). Mean change in CAT score after PR was 2.9 (5.6) points, improving by 3.8 (6.1) points in those scoring 'much better' (n=162), and by 1.3(4.5) in those who felt 'a little better' (n=88) (p=0.002). Only eight individuals reported no difference after PR and three reported feeling 'a little worse', so comparison with these smaller groups was not possible.

CONCLUSION

The CAT score is simple to implement as an outcome measure, it improves in response to PR and can distinguish categories of response.

摘要

背景

COPD(慢性阻塞性肺疾病)评估测试(CAT)是一种新引入的、易于使用的患者完成的生活质量工具,包含 8 个问题,涵盖 COPD 症状的影响。尚不清楚 CAT 评分在临床肺康复(PR)计划中的表现如何,也不知道最小临床重要差异是多少。

方法

通过伦敦各地的 PR 项目,前瞻性地研究了 CAT 评分作为一种结果测量手段的引入。它与其他措施一起使用,包括圣乔治呼吸问卷、慢性呼吸疾病问卷、临床 COPD 问卷、医院焦虑和抑郁评分、MRC(医学研究委员会)呼吸困难评分以及一系列不同的步行测试。患者完成了一个 5 分制的锚定问题,用于评估对 PR 的整体反应,从“我感觉好多了”到“我感觉更糟了”。

结果

共有 261 名 COPD 患者参与了七个项目的数据可用:平均(SD)年龄 69.0(9.0)岁,用力呼气量 1 秒(FEV1)51.1(18.7)%预计值,MRC 评分 3.2(1.0)。PR 后 CAT 评分的平均变化为 2.9(5.6)分,在评分“好得多”(n=162)的患者中改善 3.8(6.1)分,在感觉“好一点”(n=88)的患者中改善 1.3(4.5)分(p=0.002)。只有 8 人报告 PR 后没有差异,3 人报告感觉“好一点”,因此无法与这些较小的组进行比较。

结论

CAT 评分作为一种结果测量手段易于实施,它在 PR 后有所改善,可以区分反应类别。

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