个性化疼痛医学。
Individualized pain medicine.
作者信息
Kim Hyungsuk, Dionne Raymond A
机构信息
National Institute of Nursing Research, National Institutes of Health, Bethesda, MD, USA.
出版信息
Drug Discov Today Ther Strateg. 2009;6(3):83-87. doi: 10.1016/j.ddstr.2010.10.001.
Abstract
Since the first draft of the human genome was published 10 years ago, scientists have tried to develop new treatment strategies for various types of diseases based on individual genomes. It is called personalized (or individualized) medicine and is expected to increase efficacy and reduce adverse reactions of drugs. Much progress has been made with newly developed technologies, though individualized pain medicine is still far from realization. Efforts on the integrative genomic analyses along with understandings of interactions between other related factors such as environment will eventually translate complex genomic information into individualized pain medicine.
摘要
自人类基因组初稿于10年前发表以来，科学家们一直试图基于个体基因组开发针对各类疾病的新治疗策略。这被称为个性化（或个体化）医学，有望提高药物疗效并减少不良反应。尽管个性化疼痛医学仍远未实现，但新开发的技术已取得了很大进展。综合基因组分析以及对环境等其他相关因素之间相互作用的理解所做的努力，最终将把复杂的基因组信息转化为个性化疼痛医学。
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