Rüsch Dirk, Becke Karin, Eberhart Leopold H J, Franck Martin, Hönig Arnd, Morin Astrid M, Opel Sylvia, Piper Swen, Treiber Hans, Ullrich Lothar, Wallenborn Jan, Kranke Peter
Oberarzt an der Klinik für Anästhesie und Intensivtherapie des Universitätsklinikums Giessen und Marburg, Standort Marburg, Germany.
Anasthesiol Intensivmed Notfallmed Schmerzther. 2011 Mar;46(3):158-70. doi: 10.1055/s-0031-1274927. Epub 2011 Mar 11.
The aim was to update recommendations concerning the management of postoperative nausea and vomiting (PONV) for German speaking countries.
An expert panel produced evidence-based, consented statements graded according to the Scottish Intercollegiate Guidelines Network (SIGN).
Relevant risk factors for PONV include female gender, non-smoking status, history of PONV, history of motion sickness, use of intra- and postoperative opioids, volatile anesthetics and nitrous oxide. PONV scoring systems allow for an approximative risk assessment as a basis for a risk adapted approach. Since a risk-adapted prophylaxis vs. a risk-independent, fixed (combined) prophylaxis has not yet proven superior and because of inherent limitations of PONV scoring systems a fixed prophylaxis may be favourable. Regardless of the strategy for prophylaxis of PONV, high risk patients must be given a multimodal prophylaxis by avoiding known risk factors and applying multiple validated and effective antiemetic interventions. In the case of PONV immediate treatment is indicated due to its relevance for patients as well as the economic and medicolegal implications PONV may have.
Given the impact of PONV on patient satisfaction and the availability of effective and safe measures to prevent and treat PONV, further efforts should be taken to actually implement present evidence in order to improve patient?s outcome following surgical procedures.
目的是更新德语国家关于术后恶心呕吐(PONV)管理的建议。
一个专家小组制定了基于证据且经同意的声明,并根据苏格兰校际指南网络(SIGN)进行分级。
PONV的相关危险因素包括女性、不吸烟状态、PONV病史、晕动病史、术中和术后使用阿片类药物、挥发性麻醉剂和氧化亚氮。PONV评分系统可进行近似风险评估,作为风险适应性方法的基础。由于风险适应性预防与风险独立的固定(联合)预防相比尚未证明更具优势,且由于PONV评分系统存在固有局限性,固定预防可能更有利。无论PONV的预防策略如何,高危患者必须通过避免已知危险因素并采用多种经过验证且有效的止吐干预措施进行多模式预防。对于PONV,由于其对患者的影响以及可能产生的经济和法医学影响,需要进行即时治疗。
鉴于PONV对患者满意度的影响以及预防和治疗PONV的有效和安全措施的可用性,应进一步努力切实实施现有证据,以改善手术患者的预后。