Wegmann Signe Düring, Kessing Lars Vedel
Psykiatrisk Center København, Region Hovedstadens Psykiatri, Blegdamsvej 9, 2100 København Ø, Denmark.
Ugeskr Laeger. 2011 Mar 14;173(11):820-1.
Lithium has for 60 years been the main mood stabilizer for bipolar disorder and some patients have now been treated with lithium for decades without any symptoms or side effects. We present a case with excellent response to lithium during 28 years and with recurrence of a hypomania and subsequently a severe depressive episode following planned discontinuation of lithium. Discontinuation of lithium should be carefully evaluated in patients with a good response to lithium, and the specific reasons for discontinuation should be considered.
60年来，锂一直是双相情感障碍的主要心境稳定剂，一些患者现已接受锂治疗数十年，没有任何症状或副作用。我们报告一例对锂治疗28年反应良好的病例，在计划停用锂后出现轻躁狂复发，随后出现严重抑郁发作。对于对锂反应良好的患者，停用锂应仔细评估，并应考虑停药的具体原因。
