Diuresis renography. A simultaneous comparison between 131I-hippuran and 99Tcm-MAG3.

In 20 patients investigated for unilateral upper urinary tract obstruction diuresis renography was performed simultaneously with 131I-hippuran and 99Tcm-MAG3 using a gamma camera with dual isotope facilities. Furosemide was administered routinely 20 min after radionuclide injection. No significant differences were found in fractional share between the two kidneys, time to maximal activity, residual activity at 20 and 30 min, or rate of emptying after furosemide administration. The MAG3 curves showed, however, better counting statistics and on scintigrams with MAG3 more anatomic details (extent of dilation and site of obstruction) could be seen. It is concluded, that MAG3 is superior to hippuran in the evaluation of patients with possible unilateral upper urinary tract obstruction by diuresis renography.