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通过同步双通道技术对锝-99m 巯基乙酰三甘氨酸与碘-131 马尿酸进行比较。

Comparison of technetium-99m MAG3 with iodine-131 hippuran by a simultaneous dual channel technique.

作者信息

Russell C D, Thorstad B, Yester M V, Stutzman M, Baker T, Dubovsky E V

机构信息

Division of Nuclear Medicine, University of Alabama Hospital, Birmingham 35233.

出版信息

J Nucl Med. 1988 Jul;29(7):1189-93.

PMID:2969040
Abstract

Technetium-99m MAG3, a technetium-labeled analog of hippuran, was compared with [131I] hippuran using a simultaneous dual isotope study in 20 patients. The plasma clearance for MAG3 was lower than that of hippuran, but its plasma concentration was higher, resulting in similar rates of excretion and similar renal time-activity curves. Apart from better statistics with the technetium-labeled agent, there were no clinically significant differences in this group of patients.

摘要

锝-99m 巯乙酰三甘氨酸(MAG3),一种锝标记的马尿酸类似物,在20例患者中通过同时双同位素研究与[131I]马尿酸进行了比较。MAG3的血浆清除率低于马尿酸,但其血浆浓度较高,导致排泄率相似且肾时间-活性曲线相似。除了使用锝标记剂有更好的统计学结果外,该组患者中没有临床上的显著差异。

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