King’s College London (Institute of Psychiatry), Health Service and Population Research Department, Section of Epidemiology, London, UK.
J Neurol Neurosurg Psychiatry. 2011 Oct;82(10):1074-82. doi: 10.1136/jnnp.2010.234153. Epub 2011 Mar 14.
Despite the growing importance of stroke in developing countries, little is known of stroke burden in survivors. The authors investigated the prevalence of self-reported stroke, stroke-related disability, dependence and care-giver strain in Latin America (LA), China and India.
Cross-sectional surveys were conducted on individuals aged 65+ (n=15 022) living in specified catchment areas. Self-reported stroke diagnosis, disability, care needs and care giver burden were assessed using a standardised protocol. For those reporting stroke, the correlates of disability, dependence and care-giver burden were estimated at each site using Poisson or linear regression, and combined meta-analytically.
The prevalence of self-reported stroke ranged between 6% and 9% across most LA sites and urban China, but was much lower in urban India (1.9%), and in rural sites in India (1.1%), China (1.6%) and Peru (2.7%). The proportion of stroke survivors needing care varied between 20% and 39% in LA sites but was higher in rural China (44%), urban China (54%) and rural India (73%). Comorbid dementia and depression were the main correlates of disability and dependence.
The prevalence of stroke in urban LA and Chinese sites is nearly as high as in industrialised countries. High levels of disability and dependence in the other mainly rural and less-developed sites suggest underascertainment of less severe cases as one likely explanation for the lower prevalence in those settings. As the health transition proceeds, a further increase in numbers of older stroke survivors is to be anticipated. In addition to prevention, stroke rehabilitation and long-term care needs should be addressed.
尽管发展中国家的中风问题日益严重,但对于中风幸存者的负担情况却知之甚少。作者调查了拉丁美洲(LA)、中国和印度中风幸存者的自我报告中风发生率、与中风相关的残疾、依赖性和照顾者负担情况。
在指定的流域地区,对年龄在 65 岁及以上的个体进行横断面调查。使用标准化方案评估自我报告的中风诊断、残疾、护理需求和照顾者负担。对于报告中风的患者,使用泊松或线性回归在每个地点估计残疾、依赖性和照顾者负担的相关性,并进行合并的荟萃分析。
在大多数 LA 地点和中国城市,自我报告中风的发生率在 6%至 9%之间,但在印度城市(1.9%)、印度农村地区(1.1%)、中国农村地区(1.6%)和秘鲁(2.7%)则低得多。需要护理的中风幸存者比例在 LA 地点之间在 20%至 39%之间,但在中国农村(44%)、中国城市(54%)和印度农村(73%)更高。合并痴呆症和抑郁症是残疾和依赖性的主要相关因素。
在城市 LA 和中国的地点,中风的发生率与工业化国家相近。在其他主要为农村和欠发达地区,残疾和依赖性水平较高,表明在这些地区对较轻病例的确认不足,这可能是发生率较低的一个原因。随着健康转型的推进,可以预料到老年中风幸存者的人数会进一步增加。除了预防,还应解决中风康复和长期护理需求。