Koba Ai, Mori Shuichi, Ishii Norihisa
Leprosy Research Center, National Institute of Infectious Diseases 4-2-1 Aoba-cho, Higashimurayama-shi, Tokyo 189-0002, Japan.
Nihon Hansenbyo Gakkai Zasshi. 2011 Feb;80(1):11-6. doi: 10.5025/hansen.80.11.
We aimed to elucidate the patterns and trends of autochthonous leprosy in Japan from 1964 to 2009, to compare them with the findings from other studies of leprosy in decline. Data on registered leprosy cases in Japan in the period 1964-2009 were analysed with reference to trends in case detection, geographical distribution, age at diagnosis, sex, classification and family history. A consistent decline in leprosy case detection was observed in all areas of the country over the period 1964-2009. Highest incidence was consistently in Okinawa. Autochthonous leprosy has not been reported in anyone born in Japan since 1980. Increasing average age and a shift towards lower latitudes were demonstrated throughout the period. Analyses of data on autochthonous cases revealed patterns similar to those reported in other countries with declining leprosy. Okinawa has had the highest incidence of leprosy in all of Japan since the first national survey in 1900. Several possible explanations include the difference of leprosy control history between Okinawa and the rest of Japan, Okinawa's unique geographical condition, large-scale problem of stigma and discrimination against leprosy patients and delayed improvement of socio-economic conditions.
我们旨在阐明1964年至2009年日本本土麻风病的发病模式和趋势,并将其与其他关于麻风病发病率下降的研究结果进行比较。参考病例发现趋势、地理分布、诊断年龄、性别、分类和家族史,对1964 - 2009年期间日本登记的麻风病病例数据进行了分析。在1964年至2009年期间,日本所有地区的麻风病病例发现数均持续下降。发病率最高的地区一直是冲绳。自1980年以来,日本出生的人中未报告过本土麻风病病例。在此期间,平均年龄不断增加,发病地区有向低纬度地区转移的趋势。对本土病例数据的分析揭示了与其他麻风病发病率下降国家报告的模式相似的情况。自1900年首次全国调查以来,冲绳一直是日本全国麻风病发病率最高的地区。几种可能的解释包括冲绳与日本其他地区在麻风病控制历史上的差异、冲绳独特的地理条件、对麻风病患者的大规模污名化和歧视问题以及社会经济状况改善的延迟。