Office of Public Health Genomics, CDC, Atlanta, Georgia 30333, USA.
Am J Prev Med. 2011 Apr;40(4):486-93. doi: 10.1016/j.amepre.2010.12.009.
In spite of accelerating human genome discoveries in a wide variety of diseases of public health significance, the promise of personalized health care and disease prevention based on genomics has lagged behind. In a time of limited resources, public health agencies must continue to focus on implementing programs that can improve health and prevent disease now. Nevertheless, public health has an important and assertive leadership role in addressing the promise and pitfalls of human genomics for population health. Such efforts are needed not only to implement what is known in genomics to improve health but also to reduce potential harm and create the infrastructure needed to derive health benefits in the future.
尽管在许多具有公共卫生意义的疾病中，人类基因组的发现速度正在加快，但基于基因组学的个性化医疗保健和疾病预防的前景仍落后于实际。在资源有限的情况下，公共卫生机构必须继续专注于实施能够改善健康和预防疾病的项目。尽管如此，公共卫生部门在解决人类基因组学对人口健康的承诺和陷阱方面仍发挥着重要和积极的领导作用。不仅需要这些努力来实施已知的基因组学知识以改善健康，还需要减少潜在的危害并为未来获得健康益处创造必要的基础设施。
