Department of Radiology and Cardiology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie 514-8507, Japan.
Radiology. 2011 May;259(2):384-92. doi: 10.1148/radiol.11101323. Epub 2011 Mar 15.
To compare the imaging time and image quality obtained with whole-heart coronary magnetic resonance (MR) angiography performed with five- and 32-channel coils in healthy subjects and determine the accuracy of MR angiography performed with 32-channel coils in the detection of obstructive coronary artery disease (CAD).
The institutional review board approved the study protocol, and all participants provided written informed consent. The authors studied 10 healthy subjects and 67 patients suspected of having CAD who were scheduled for coronary angiography. Unenhanced 1.5-T coronary MR angiography was performed with five- and 32-channel coils in healthy subjects and with 32-channel coils in patients. Clinically significant CAD was defined as a diameter reduction of at least 50% at coronary angiography. The sensitivity and specificity of coronary MR angiography were calculated.
The mean imaging time was substantially reduced from 12.3 minutes ± 4.2 (standard deviation) with five-channel coils to 6.3 minutes ± 2.2 with 32-channel coils, with equivalent image quality scores. Acquisition of MR angiograms was completed in all 67 patients, with a mean imaging time of 6.2 minutes ± 2.8. The prevalence of CAD in the study population was 58% (39 of the 67 patients). The areas under the receiver operating characteristic curves as determined at vessel- and patient-based analyses were 0.91 and 0.90, respectively; the sensitivity and specificity at vessel-based analysis were 86% and 93%, respectively.
Whole-heart coronary MR angiography performed at 1.5 T with 32-channel coils permits noninvasive detection of CAD with substantially reduced imaging time. This noninvasive approach can be an alternative to multidetector computed tomographic coronary angiography for ruling out obstructive CAD in patients who have a contraindication to contrast material and in young subjects who are at higher risk from ionizing radiation.
http://radiology.rsna.org/lookup/suppl/doi:10.1148/radiol.11101323/-/DC1.
比较在健康志愿者中使用 5 通道和 32 通道线圈进行全心冠状动脉磁共振（MR）血管造影的成像时间和图像质量，并确定 32 通道线圈进行 MR 血管造影在检测阻塞性冠状动脉疾病（CAD）中的准确性。
机构审查委员会批准了该研究方案，所有参与者均提供了书面知情同意书。作者研究了 10 名健康志愿者和 67 名疑似 CAD 的患者，这些患者计划进行冠状动脉造影。在健康志愿者中使用 5 通道和 32 通道线圈进行无增强 1.5-T 冠状动脉 MR 血管造影，在患者中仅使用 32 通道线圈进行。临床显著 CAD 的定义为冠状动脉造影时至少有 50%的直径减少。计算了冠状动脉 MR 血管造影的敏感性和特异性。
从使用 5 通道线圈的 12.3 分钟±4.2（标准差），成像时间明显缩短至使用 32 通道线圈的 6.3 分钟±2.2，而图像质量评分相同。所有 67 例患者均完成了 MR 血管造影采集，平均成像时间为 6.2 分钟±2.8。研究人群中 CAD 的患病率为 58%（39 例患者）。基于血管和患者的分析的受试者工作特征曲线下面积分别为 0.91 和 0.90，基于血管的分析的敏感性和特异性分别为 86%和 93%。
在 1.5 T 下使用 32 通道线圈进行全心冠状动脉 MR 血管造影，可以非侵入性地检测 CAD，同时显著缩短成像时间。这种非侵入性方法可以替代多排 CT 冠状动脉造影，用于排除对造影剂有禁忌症的患者和因电离辐射而处于更高风险的年轻患者的阻塞性 CAD。
http://radiology.rsna.org/lookup/suppl/doi:10.1148/radiol.11101323/-/DC1.
