Department of Audiology and Phoniatrics, Nofer Institute of Occupational Medicine, Lodz, Poland.
J Occup Environ Med. 2011 Apr;53(4):441-7. doi: 10.1097/JOM.0b013e3182143f46.
The aim of this study was to assess the balance and vestibular systems in healthy workers exposed to low concentrations of organic solvent mixtures.
The study groups comprised 60 workers exposed to mixture of organic solvents and 110 reference workers. All subjects performed static posturography and electronystagmography (ENG).
In posturography, abnormal reaction time was more frequent and statistically longer in solvent-exposed group. Also, worse results of movement coordination parameters were observed in this group. The ENG square waves and abnormal optokinetic results were more common in exposed group. Mean caloric response was shorter in the exposed group. Negative relationship was found between time of caloric response and cumulative toluene concentration.
Balance abnormalities in solvent-exposed workers indicated subclinical damage, mainly of central part of vestibular system and body-movement coordination. It would not be reasonable to exclude the vestibular hyporeactivity.
本研究旨在评估接触低浓度有机溶剂混合物的健康工人的平衡和前庭系统。
研究组包括 60 名接触有机溶剂混合物的工人和 110 名参照工人。所有受试者均进行静态姿势描记术和眼震电图(ENG)检查。
在姿势描记术中,暴露组的异常反应时间更频繁且统计学上更长。此外,该组的运动协调参数结果更差。暴露组的 ENG 方波和异常视动结果更为常见。暴露组的冷刺激反应时间更短。冷刺激反应时间与累积甲苯浓度呈负相关。
暴露于溶剂的工人的平衡异常表明存在亚临床损害,主要是前庭系统和身体运动协调的中枢部分受损。不能排除前庭反应迟钝。