Dr. Tapas Kumar Aich, DPM., MD., Assistant professor of Psychiatry, Universal College of Medical Sciences, PB-53, Ranigaon, Bhairahawa, Nepal.
Indian J Psychiatry. 2001 Jul;43(3):246-51.
We had reported earlier (1998) a high percentage of moderate to severe EEG abnormalities (43.75% of cases) amongst adolescent manic population. Sixteen adolescent manics, with a mean age of 14 9 years, diagnosed according to ICD-10 were taken up for the initial study. Present study is the three-year follow-up report of 67.75% (11 out of 16) of the original patient population. All these patients were subjected fc 21-channel EEG and anticonvulsant drugs were started to all. Follow-up data showed that 3 out of 6 patients, who discontinued medications, were relapsed during this 3 years period. But none of the 5 patients, who regularly took prescribed medicines, relapsed during the same period. Significance of these findings in relapse prevention and the role of anticonvulsants, particularly in relation to adolescent mania, have been emphasized.
我们曾在早些时候（1998 年）报告过，青少年躁狂患者中存在较高比例的中重度脑电图异常（占病例的 43.75%）。我们对 16 名符合 ICD-10 标准的青少年躁狂症患者进行了初步研究，这些患者的平均年龄为 14.9 岁。本研究是对原始患者群体中 67.75%（16 名患者中的 11 名）的三年随访报告。所有这些患者都接受了 21 通道脑电图检查，并为所有患者开始使用抗癫痫药物。随访数据显示，在这 3 年期间，3 名停止用药的患者中有 3 名复发。但在同一时期，5 名定期服用规定药物的患者中没有一人复发。这些发现对于预防复发的意义以及抗癫痫药物的作用，特别是在青少年躁狂症方面，已得到强调。
