Geller B, Sun K, Zimerman B, Luby J, Frazier J, Williams M
Washington University School of Medicine, St Louis, MO 63110, USA.
J Affect Disord. 1995 Aug 18;34(4):259-68. doi: 10.1016/0165-0327(95)00023-g.
26 subjects aged 7-18 years were studied. Diagnoses of bipolar disorders were established using the Kiddie-Schedule for Affective Disorders and Schizophrenia-Present Episode Version-1986 modified for DSM-III-R criteria and for rating the number and duration of manic and hypomanic episodes. Complex cycling patterns were observed. These included numerous brief episodes suggesting continuous rapid-cycling in 80.8% of cases. Mean age of onset was early (8.5 +/- 4.4 years). Psychotic phenomena, suicidality, hyperactivity and 'mixed mania' were highly prevalent. Data in this report provide support for complex and rapid-cycling patterns in childhood onset bipolar disorder.
对26名年龄在7至18岁的受试者进行了研究。使用根据《精神疾病诊断与统计手册》第三版修订版标准修改的《儿童情感障碍和精神分裂症评定量表-当前发作版本-1986》来确定双相情感障碍的诊断，并对躁狂和轻躁狂发作的次数和持续时间进行评分。观察到复杂的循环模式。其中包括大量短暂发作，提示80.8%的病例存在持续快速循环。平均发病年龄较早（8.5±4.4岁）。精神病性现象、自杀倾向、多动和“混合性躁狂”非常普遍。本报告中的数据为儿童期起病的双相情感障碍中的复杂和快速循环模式提供了支持。
