Sarwar Iram, Sultana Ruqqia, Nisa Rahat Un, Qayyum Iftikhar
Department of Obstetric and Gynaecology, Ayub Teaching Hospital Abbottabad, Pakistan.
J Ayub Med Coll Abbottabad. 2010 Jan-Mar;22(1):7-10.
Vaginal agenesis is congenital anomaly of the female genital tract and may occur as isolated developmental defect or as part of a complex of anomalies. The aim of this study was to determine the effectiveness of vaginoplasty by using amnion as graft in the creation of neovagina for patients with Mayor-Rokitansky-Kuster-Hauser Syndrome.
this is a retrospective study of 28 cases of vaginal agenesis associated with Mayor-Rokitansky-Kuster-Hauser Syndrome, over the period of 20 years, in which vaginoplasty was done by modified McIndoe procedure by using amnion as graft.
vaginoplasty using amnion graft was successfully performed in all except one case in which rectum got opened and procedure was abandoned after the repair of rectum. The functional results were quite satisfactory. Except one case none had any significant peri-operative complication. Post surgical results were acceptable to the patients sexually and aesthetically.
Although new techniques of vaginoplasty have evolved over the years using laparoscopic approach and by use of different materials as graft, vaginoplasty with amnion graft is still a safe and effective procedure to treat patients of vaginal agenesis. The technique is simple and safe and provides a satisfactory and functional vagina in majority of the patients.
阴道闭锁是女性生殖道的先天性异常，可作为孤立的发育缺陷出现，或作为异常综合征的一部分。本研究的目的是确定在为 Mayer-Rokitansky-Kuster-Hauser 综合征患者创建新阴道时使用羊膜作为移植物进行阴道成形术的有效性。
这是一项对 28 例与 Mayer-Rokitansky-Kuster-Hauser 综合征相关的阴道闭锁病例进行的回顾性研究，为期 20 年，其中通过改良的 McIndoe 手术使用羊膜作为移植物进行阴道成形术。
除 1 例直肠被切开，在直肠修复后手术被放弃外，所有病例均成功进行了使用羊膜移植物的阴道成形术。功能结果相当令人满意。除 1 例患者外，均无任何明显的围手术期并发症。术后结果在性和美观方面患者均可接受。
尽管多年来阴道成形术的新技术不断发展，采用腹腔镜方法并使用不同材料作为移植物，但使用羊膜移植物进行阴道成形术仍然是治疗阴道闭锁患者的一种安全有效的方法。该技术简单安全，在大多数患者中可提供令人满意且功能良好的阴道。
