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泌尿外科中的羊膜治疗生物材料:当前及未来应用

Amniotic therapeutic biomaterials in urology: current and future applications.

作者信息

Oottamasathien Siam, Hotaling James M, Craig James R, Myers Jeremy B, Brant William O

机构信息

Department of Surgery and Section of Pediatric Urology, University of Utah, Salt Lake City, Utah, USA.

Primary Children's Hospital, University of Utah, Salt Lake City, Utah, USA.

出版信息

Transl Androl Urol. 2017 Oct;6(5):943-950. doi: 10.21037/tau.2017.09.01.

DOI:10.21037/tau.2017.09.01
PMID:29184795
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5673810/
Abstract

To examine the rationale and applications of amniotic tissue augmentation in urological surgery. Published literature in English-language was reviewed for basic science and clinical use of amniotic or amnion-chorionic tissue in genitourinary tissues. Basic science and animal studies support the likely benefit of clinical applications of amnion-derived tissues in a variety of urologic interventions. The broad number of properties found in amniotic membrane, coupled with its immunologically privileged status presents a number of future applications in the urological surgical realm. These applications are in their clinical infancy and suggest that further studies are warranted to investigate the use of these products in a systematic fashion.

摘要

探讨羊膜组织增强技术在泌尿外科手术中的基本原理及应用。检索了英文发表文献,以了解羊膜或羊膜 - 绒毛膜组织在泌尿生殖组织中的基础科学研究及临床应用情况。基础科学研究和动物实验表明,羊膜来源组织在多种泌尿外科手术干预中可能具有临床应用价值。羊膜具有多种特性,加之其免疫赦免状态,在泌尿外科手术领域展现出诸多未来应用前景。这些应用尚处于临床初期阶段,提示有必要开展进一步研究,以系统地探究这些产品的应用。

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