Buiza Cristina, Navarro Ana, Díaz-Orueta Unai, González Mari Feli, Alaba Javier, Arriola Enrique, Hernández Carmen, Zulaica Amaia, Yanguas José Javier
Fundación Instituto Gerontológico Matia-INGEMA, Donostia-San Sebastián, Guipúzcoa, España.
Rev Esp Geriatr Gerontol. 2011 May-Jun;46(3):131-8. doi: 10.1016/j.regg.2010.09.006. Epub 2011 Mar 21.
The cognitive assessment of patients with advanced dementia needs proper screening instruments that allow obtain information about the cognitive state and resources that these individuals still have. The present work conducts a Spanish validation study of the Severe Mini Mental State Examination (SMMSE).
Forty-seven patients with advanced dementia (Mini-Cognitive Examination [MEC]<11) were evaluated with the Reisberg's Global Deterioration Scale, MEC, SMMSE and Severe Cognitive Impairment Profile scales.
All test items were discriminative. The test showed high internal (α=0.88), test-retest (0.64 to 1.00, P<.01) and between observers reliabilities (0.69-1.00, p<0.01), both for scores total and for each item separately. Construct validity was tested through correlations between the instrument and MEC scores (r=0.59, P<0.01). Further information on the construct validity was obtained by dividing the sample into groups that scored above or below 5 points in the MEC and recalculating their correlations with SMMSE. The correlation between the scores in the SMMSE and MEC was significant in the MEC 0-5 group (r=0.55, P<.05), but not in the MEC>5 group. Additionally, differences in scores were found in the SMMSE, but not in the MEC, between the three GDS groups (5, 6 and 7) (H=11.1, P<.05).
The SMMSE is an instrument for the assessment of advanced cognitive impairment which prevents the floor effect through an extension of lower measurement range relative to that of the MEC. From our results, this rapid screening tool and easy to administer, can be considered valid and reliable.
对晚期痴呆患者进行认知评估需要合适的筛查工具,以便获取这些个体的认知状态及尚存能力的信息。本研究对简易精神状态检查量表(SMMSE)进行了西班牙语版本的效度验证。
对47例晚期痴呆患者(简易认知检查量表[MEC]<11)使用雷斯伯格总体衰退量表、MEC、SMMSE和严重认知障碍概况量表进行评估。
所有测试项目均具有鉴别性。该测试在总分及各项目上均显示出较高的内部信度(α=0.88)、重测信度(0.64至1.00,P<0.01)及观察者间信度(0.69 - 1.00,P<0.01)。通过该工具与MEC评分之间的相关性检验建构效度(r=0.59,P<0.01)。通过将样本分为MEC评分高于或低于5分的组,并重新计算其与SMMSE的相关性,获得了关于建构效度的更多信息。SMMSE与MEC评分之间的相关性在MEC 0 - 5分组中显著(r=0.55,P<0.05),但在MEC>5分组中不显著。此外,在SMMSE中发现了三个总体衰退量表分组(5、6和7)之间的评分差异,但在MEC中未发现(H=11.1,P<0.05)。
SMMSE是一种用于评估晚期认知障碍的工具,相对于MEC,它通过扩展较低测量范围避免了地板效应。根据我们的结果,这种快速筛查工具易于实施,可认为是有效且可靠的。