Guo Y C
Xijing Hospital, Fourth Military Medical University, Xi'an.
Zhonghua Zhong Liu Za Zhi. 1990 Jan;12(1):75-7.
The killing effects of 514.5 nm argon laser and 630 nm dye laser radiation on the murine SP2/0 myeloma cells cultured in thin layer containing HPD were measured by clonogenic assay. It was found that the former was 3.34 fold higher than the latter. Improved argon laser photodynamic therapy was used in the treatment of 104 superficial bladder tumors in 40 patients. Firstly, high output (6-7 W/cm2) argon laser contact and interstitial radiation were used to eradicate visible tumors, and then cylindrical optic fiber was used to deliver argon laser (2.1-3.47 W/cm2) for whole bladder mucosal scattered irradiation to destroy small multi-focal tumors and reduce recurrence. In this series, the follow-up was 7-34 months. All patients achieved complete response and only 7 (17.5%) recurred.
采用克隆形成试验测定了514.5nm氩离子激光和630nm染料激光在含血卟啉衍生物（HPD）的薄层中对培养的小鼠SP2/0骨髓瘤细胞的杀伤作用。结果发现，前者的杀伤作用比后者高3.34倍。改良的氩离子激光光动力疗法用于治疗40例患者的104例浅表性膀胱肿瘤。首先，使用高输出（6 - 7W/cm²）的氩离子激光接触和间质照射以根除可见肿瘤，然后使用圆柱形光纤传输氩离子激光（2.1 - 3.47W/cm²）对整个膀胱黏膜进行散射照射，以破坏小的多灶性肿瘤并降低复发率。在该系列研究中，随访时间为7 - 34个月。所有患者均达到完全缓解，仅7例（17.5%）复发。
