School of Humanities and Sciences, Stanford University, Stanford, CA, USA.
Dermatol Clin. 2011 Apr;29(2):287-96, x. doi: 10.1016/j.det.2011.01.004.
The use of radiation therapy in the management of skin cancer is variable and often anecdotal. Applied as both primary and adjuvant therapy in patients with both nonmelanoma skin cancer and rarer tumors of the skin, a consensus regarding optimal dosing regimens has not yet been reached. Herein, the authors outline the basic concepts of radiation therapy for tumors of the skin and review its use for high-risk nonmelanoma skin cancer, as well as less common malignancies, including angiosarcoma, Merkel cell carcinoma, and sebaceous carcinoma.
放射治疗在皮肤癌的治疗中应用不一，且多为经验性治疗。放射治疗可作为非黑色素瘤皮肤癌和更罕见皮肤肿瘤的初始治疗和辅助治疗，目前尚未就最佳剂量方案达成共识。本文作者概述了皮肤肿瘤放射治疗的基本概念，并回顾了其在高危非黑色素瘤皮肤癌以及包括血管肉瘤、默克尔细胞癌和皮脂腺癌等较少见恶性肿瘤中的应用。
