Hishida H, Sakabe Y, Kawamura K, Hagiwara K, Murashima Y, Kodama K, Sugiura Y, Koyama Y, Tamagaki H, Fukui M
Department of Internal Medicine, Fujita Health University School of Medicine, Toyoake, Japan.
Jpn Circ J. 1990 Mar;54(3):316-21. doi: 10.1253/jcj.54.316.
Two-dimensional echocardiograms of parasternal long-axis view were recorded and the mean echo intensity and its distribution in the interventricular septum were examined for the purpose of inferring myocardial tissue. Six healthy subjects (N), 29 with left ventricular hypertrophy (LVH), and 12 with old anteroseptal myocardial infarctions (MI) were used in the study. Settings for gain control were adjusted in the constant manner. Data were recorded on a Video tape recorder, with analog data converted to digital signals, subjected to a low-pass filtering, and then analyzed by a Computer tomography image processor. The region of interest was set within the interventricular septum, and a mean relative echo intensity and its histogram (number of pixels showing different echo intensity) was evaluated. The histogram patterns were examined and the parameter for skewness, which shows asymmetrical characteristics, and the parameter for kurtosis, which shows degree of peakedness of distribution, were calculated. Relative echo intensity was found to increase in the order MI greater than LVH greater than N. Histograms showed the majority of pixels were concentrated at the low echo intensity level in the normal group, while pixels were distributed in a relatively gentle slope around the mean value in the LVH group. Many pixels were in the high intensity levels in the MI group, although the rest were dispersed throughout various intensities including low level. The differences are thought to be related to the extent and density of fibrosis. Analysis of two-dimensional echocardiographic echo intensity and distribution may be useful in characterizing myocardial tissues.
记录胸骨旁长轴视图的二维超声心动图，并检查室间隔的平均回声强度及其分布，以推断心肌组织。本研究使用了6名健康受试者（N）、29名左心室肥厚（LVH）患者和12名陈旧性前间隔心肌梗死（MI）患者。增益控制设置以恒定方式调整。数据记录在磁带录像机上，模拟数据转换为数字信号，进行低通滤波，然后由计算机断层图像处理器进行分析。感兴趣区域设置在室间隔内，并评估平均相对回声强度及其直方图（显示不同回声强度的像素数量）。检查直方图模式，并计算显示不对称特征的偏度参数和显示分布峰值程度的峰度参数。发现相对回声强度按MI大于LVH大于N的顺序增加。直方图显示，正常组中大多数像素集中在低回声强度水平，而LVH组中像素围绕平均值分布在相对平缓的斜率上。MI组中许多像素处于高强度水平，尽管其余像素分散在包括低水平在内的各种强度中。这些差异被认为与纤维化的程度和密度有关。二维超声心动图回声强度和分布的分析可能有助于表征心肌组织。
