Ieki K, Imataka K, Sakurai S, Okamoto E, Ashida T, Fujii J
Institute for Adult Diseases, Asahi Life Foundation, Tokyo.
J Cardiol. 1996 Jun;27(6):309-14.
The patterns of interventricular septal hypertrophy were analyzed on two-dimensional echocardiograms to differentiate hypertrophic cardiomyopathy (HCM) from hypertensive cardiac hypertrophy. The control group comprised 110 patients without cardiovascular disease who were matched for age and gender with the hypertension group. The hypertension group comprised 110 patients with uncomplicated essential hypertension, and the HCM group comprised 32 patients in whom the wall thickness of the interventricular septum was 12 mm or more at the mid-portion and no underlying heart disease responsible for cardiac hypertrophy was detected. The interventricular septal thickness was measured both at the thickest portion within 15 mm distal to the aortoseptal junction (basal portion: B) and at the mid-portion (M) in the end-diastolic image on the left parasternal long-axis tomograms, and the B/M ratio was calculated in each patient. The B/M ratio was 1.07 +/- 0.16 in the control group, 1.19 +/- 0.18 in the hypertension group, and 0.83 +/- 0.12 in the HCM group. Compared with the control group, the B/M ratio was significantly high in the hypertension group (p < 0.05) and significantly low in the HCM group (p < 0.01). These results indicate that hypertrophy of the interventricular septum is dominant at the basal portion in hypertensive patients but at the mid-portion in patients with HCM.
在二维超声心动图上分析室间隔肥厚的模式，以区分肥厚型心肌病（HCM）和高血压性心脏肥厚。对照组由110名无心血管疾病的患者组成，他们在年龄和性别上与高血压组相匹配。高血压组由110名患有单纯原发性高血压的患者组成，HCM组由32名患者组成，这些患者室间隔中部厚度为12mm或更厚，且未检测到导致心脏肥厚的潜在心脏病。在胸骨旁左心室长轴断层图像的舒张末期图像中，在主动脉-室间隔交界处远端15mm内的最厚部分（基部：B）和中部（M）测量室间隔厚度，并计算每位患者的B/M比值。对照组的B/M比值为1.07±0.16，高血压组为1.19±0.18，HCM组为0.83±0.12。与对照组相比，高血压组的B/M比值显著升高（p<0.05），HCM组显著降低（p<0.01）。这些结果表明，高血压患者室间隔肥厚在基部占主导，而HCM患者在中部占主导。
