Kawamura K, Hishida H, Sakabe Y, Hagiwara K, Murashima Y, Kodama K, Sugiura Y, Koyama Y, Mizuno Y
Department of Internal Medicine, Fujita-Gakuen Health University School of Medicine, Toyoake.
J Cardiol. 1987 Mar;17(1):149-57.
To assess myocardial tissue changes, the distribution of echo intensities of two-dimensional echocardiograms was analyzed using a histogram. The materials were obtained from six normal subjects (N), 29 patients with left ventricular hypertrophy (LVH), and 12 patients one year or more after the onset of anteroseptal myocardial infarction (MI). A transducer with a central frequency of 2.3 MHz was used. Scanner receiver settings, including sensitivity-time control, were kept constant for all subjects. The parasternal long-axis image was digitized and computer-processed. The region of interest was located within the interventricular septum. The mean echo intensity and its distribution were studied. The shape of the histogram was evaluated for skewness and kurtosis. Relative echo intensity: N = 0.23 +/- 0.07 (mean +/- SD) less than LVH = 0.58 +/- 0.18 less than MI = 1.07 +/- 0.25 (p less than 0.01). Skewness: N = 1.58 +/- 0.63 greater than LVH = 0.60 +/- 0.61 greater than MI = -0.14 +/- 0.43 (p less than 0.01). Kurtosis: N = 18.0 +/- 7.3 greater than LVH = 10.5 +/- 3.3 greater than MI = 7.7 +/- 0.9 (p less than 0.01). These differences may closely relate to an increase in collagen fiber content. Consequently, analysis of the myocardial echo intensity distribution, in addition to mean echo intensities, may become a clinically useful approach for identifying myocardial tissue changes.
为评估心肌组织变化，使用直方图分析二维超声心动图的回声强度分布。材料取自6名正常受试者（N）、29名左心室肥厚（LVH）患者以及12名前间隔心肌梗死（MI）发病一年或更长时间后的患者。使用中心频率为2.3 MHz的换能器。所有受试者的扫描仪接收器设置（包括灵敏度时间控制）保持恒定。将胸骨旁长轴图像数字化并进行计算机处理。感兴趣区域位于室间隔内。研究平均回声强度及其分布。评估直方图的形状以确定偏度和峰度。相对回声强度：N = 0.23±0.07（平均值±标准差）＜LVH = 0.58±0.18＜MI = 1.07±0.25（p＜0.01）。偏度：N = 1.58±0.63＞LVH = 0.60±0.61＞MI = -0.14±0.43（p＜0.01）。峰度：N = 18.0±7.3＞LVH = 10.5±3.3＞MI = 7.7±0.9（p＜0.01）。这些差异可能与胶原纤维含量增加密切相关。因此，除平均回声强度外，分析心肌回声强度分布可能成为识别心肌组织变化的一种临床有用方法。
