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创伤后6至9年的长期生存及与健康相关的生活质量

Long-term survival and health-related quality of life 6 to 9 years after trauma.

作者信息

Overgaard Mikkel, Høyer Christian Bjerre, Christensen Erika Frischknecht

机构信息

Trauma Center, Aarhus University Hospital, Aarhus C, Denmark.

出版信息

J Trauma. 2011 Aug;71(2):435-41. doi: 10.1097/TA.0b013e31820e7ec3.

Abstract

BACKGROUND

Trauma systems have improved short-term survival of the severely injured but knowledge on long-term outcome is limited. This study aimed to assess outcome 6 years to 9 years after moderate to severe injury in terms of survival, Health-Related Quality of Life (HRQOL) and employment status.

METHODS

Patients admitted to Aarhus Level I Trauma Center in 1998 to 2000, aged 15 years or more, with an Injury Severity Score (ISS) ≥9 were included. Patients were divided into three groups based on ISS (ISS, 9-15; ISS, 16-24; ISS >24). Survival status was obtained from the Danish Central Person Registry. HRQOL was measured with the Short Form 36 (SF-36) questionnaire, which was mailed to survivors 6 years to 9 years after admission and compared with a matched control group.

RESULTS

Three hundred twenty-two patients were included. Seventy-one percentage were men, median age was 34 years (range, 15-89 years), median ISS was 17 (range, 9-75). In-hospital survival was 85%. After a median of 7.3 years, overall survival was 78%. After hospital discharge, no difference in survival was found between the three patient groups.Sixty-nine percentage of the contacted patients completed the SF-36. Mean SF-36 scores were significantly lower in the patient group than in the control group in all eight SF-36 domains (p < 0.001). Return to employment or education was 52%, whereas 20% of the patients reported to be on early retirement.

CONCLUSION

Six years to nine years after traumatic injury, 78% of the patients were alive. HRQOL was significantly lower for injured patients than a matched control group. Twenty percentage of the patients retired early.

摘要

背景

创伤系统已改善了重伤患者的短期生存率,但关于长期预后的知识有限。本研究旨在从中度至重度损伤后6至9年的生存、健康相关生活质量(HRQOL)和就业状况方面评估预后。

方法

纳入1998年至2000年入住奥胡斯一级创伤中心、年龄15岁及以上、损伤严重程度评分(ISS)≥9的患者。根据ISS将患者分为三组(ISS,9 - 15;ISS,16 - 24;ISS > 24)。生存状况从丹麦中央人口登记处获取。采用简短健康调查问卷(SF - 36)对HRQOL进行测量,该问卷在患者入院6至9年后邮寄给幸存者,并与匹配的对照组进行比较。

结果

共纳入322例患者。71%为男性,中位年龄为34岁(范围15 - 89岁),中位ISS为17(范围9 - 75)。住院生存率为85%。中位7.3年后,总生存率为78%。出院后,三组患者的生存率无差异。69%的受访患者完成了SF - 36问卷。在SF - 36的所有八个领域中,患者组的平均SF - 36评分均显著低于对照组(p < 0.001)。恢复工作或上学的比例为52%,而20%的患者报告提前退休。

结论

创伤后6至9年,78%的患者存活。受伤患者的HRQOL显著低于匹配的对照组。20%的患者提前退休。

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