School of Medicine, University of Queensland, Brisbane, Q 4029, Australia.
J Affect Disord. 2011 Jul;132(1-2):223-30. doi: 10.1016/j.jad.2011.02.023. Epub 2011 Mar 22.
Generalized anxiety disorder (GAD) occurs commonly, with widespread consequences including decreased functioning and wellbeing, and increased consumption of health resources. Notwithstanding its prevalence and impact, knowledge about GAD in older adults is still scarce. Accordingly, the main goals of this study were to estimate the prevalence and analyze the correlates of 12-month DSM-IV GAD in older community-residing adults.
The sample was drawn from the 2007 Australian National Survey of Mental Health and Well-Being and consisted of 3035 participants aged between 55 and 85years, assessed by lay interviewers with the fully-structured Composite International Diagnostic Interview.
Eighty-four participants were diagnosed with GAD, equivalent to a weighted 12-month population prevalence of 2.8% (95% CI: 2.0, 3.7). In a multivariate logistic regression model older age (OR=0.24, p=0.006), functional limitations (OR=1.07, p=0.001), lifetime depression comorbidity (OR=5.31, p<0.001), concerns about having a serious illness despite doctor's reassurance (OR=2.29, p=0.021), and family history of anxiety or depression (OR=2.41, p=0.007) were the most significant predictors of 12-month GAD in older adults.
This was a cross sectional study, limiting causal inferences.
In community-residing older adults GAD is highly prevalent and strongly associated with functional limitations, psychiatric comorbidity and increased medication intake. These findings suggest the need for greater clinical awareness of GAD among older adults.
广泛性焦虑障碍(GAD)较为常见,其广泛后果包括功能下降和幸福感降低,以及卫生资源消耗增加。尽管 GAD 较为普遍且影响较大,但老年人对 GAD 的了解仍然有限。因此,本研究的主要目的是估计老年人中 12 个月 DSM-IV GAD 的患病率,并分析其相关因素。
该样本来自 2007 年澳大利亚国家心理健康和幸福感调查,由 3035 名年龄在 55 至 85 岁之间的参与者组成,由经过培训的访谈员使用完全结构化的复合国际诊断访谈进行评估。
84 名参与者被诊断患有 GAD,加权 12 个月人群患病率为 2.8%(95%CI:2.0,3.7)。在多变量逻辑回归模型中,年龄较大(OR=0.24,p=0.006)、功能受限(OR=1.07,p=0.001)、终生抑郁共病(OR=5.31,p<0.001)、尽管医生已保证但仍担心患有严重疾病(OR=2.29,p=0.021)和有焦虑或抑郁家族史(OR=2.41,p=0.007)是老年人 12 个月 GAD 的最重要预测因素。
这是一项横断面研究,限制了因果推断。
在社区居住的老年人中,GAD 患病率很高,与功能受限、精神共病和增加药物使用密切相关。这些发现表明,老年人需要更加关注 GAD。