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使用可控低剂量伽马射线辐照对用于前交叉韧带重建的同种异体肌腱进行灭菌：生物力学与临床视角

Use of controlled low dose gamma irradiation to sterilize allograft tendons for ACL reconstruction: biomechanical and clinical perspective.

作者信息

Samsell Brian J, Moore Mark A

机构信息

LifeNet Health, 1864 Concert Drive, Virginia Beach, VA 23453, USA.

出版信息

Cell Tissue Bank. 2012 Jun;13(2):217-23. doi: 10.1007/s10561-011-9251-7. Epub 2011 Mar 23.

DOI:10.1007/s10561-011-9251-7
PMID:21431365
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3350629/
Abstract

As reviewed here, numerous biomechanical and clinical studies support the use of controlled, low temperature irradiation of allograft tendons, to provide both excellent clinical results and medical-device grade sterile allografts with minimal risk of disease transmission.

摘要

正如本文所综述的，大量生物力学和临床研究支持对同种异体肌腱进行可控低温照射，以获得优异的临床效果，并提供医疗器械级无菌同种异体移植物，同时将疾病传播风险降至最低。

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本文引用的文献

1
Inactivation of enveloped and non-enveloped viruses on seeded human tissues by gamma irradiation.通过伽马射线辐照使接种于人体组织上的包膜病毒和无包膜病毒失活。
Cell Tissue Bank. 2012 Aug;13(3):401-7. doi: 10.1007/s10561-011-9266-0. Epub 2011 Aug 3.
2
Does the graft source really matter in the outcome of patients undergoing anterior cruciate ligament reconstruction? An evaluation of autograft versus allograft reconstruction results: a systematic review.在接受前交叉韧带重建的患者中，移植物来源真的会影响结果吗？自体移植物与同种异体移植物重建结果的评估：系统评价。
Am J Sports Med. 2010 Jan;38(1):189-99. doi: 10.1177/0363546509356530.
3
Anterior cruciate ligament reconstruction with BPTB autograft, irradiated versus non-irradiated allograft: a prospective randomized clinical study.自体骨-髌腱-骨移植前交叉韧带重建术：辐照同种异体移植物与未辐照同种异体移植物的前瞻性随机临床研究
Knee Surg Sports Traumatol Arthrosc. 2009 May;17(5):464-74. doi: 10.1007/s00167-008-0714-8. Epub 2009 Jan 13.
4
A retrospective comparison of the incidence of bacterial infection following anterior cruciate ligament reconstruction with autograft versus allograft.自体移植与异体移植前交叉韧带重建术后细菌感染发生率的回顾性比较。
Arthroscopy. 2008 Dec;24(12):1330-5. doi: 10.1016/j.arthro.2008.07.015. Epub 2008 Sep 13.
5
Effect of low dose and moderate dose gamma irradiation on the mechanical properties of bone and soft tissue allografts.低剂量和中等剂量γ射线辐照对骨和软组织同种异体移植物力学性能的影响。
Cell Tissue Bank. 2008 Dec;9(4):289-98. doi: 10.1007/s10561-008-9069-0. Epub 2008 Apr 23.
6
The effect of donor age and low-dose gamma irradiation on the initial biomechanical properties of human tibialis tendon allografts.供体年龄和低剂量伽马射线照射对人胫骨肌腱同种异体移植物初始生物力学特性的影响。
Am J Sports Med. 2008 Jul;36(7):1358-66. doi: 10.1177/0363546508314394. Epub 2008 Apr 9.
7
Nonirradiated versus irradiated Achilles allograft: in vivo failure comparison.未辐照与辐照后的跟腱同种异体移植：体内失效比较
Am J Sports Med. 2007 Oct;35(10):1653-8. doi: 10.1177/0363546507302926. Epub 2007 May 21.
8
A meta-analysis of stability of autografts compared to allografts after anterior cruciate ligament reconstruction.前交叉韧带重建术后自体移植物与异体移植物稳定性的荟萃分析。
Knee Surg Sports Traumatol Arthrosc. 2007 Jul;15(7):851-6. doi: 10.1007/s00167-007-0328-6. Epub 2007 Apr 17.
9
A literature review of autograft and allograft anterior cruciate ligament reconstruction.自体移植物和同种异体移植物前交叉韧带重建的文献综述。
Knee Surg Sports Traumatol Arthrosc. 2007 Jun;15(6):690-704. doi: 10.1007/s00167-006-0236-1. Epub 2007 Apr 12.
10
The impact of irradiation on the microbiological safety, biomechanical properties, and clinical performance of musculoskeletal allografts.
Orthopedics. 2006 Nov;29(11):991-6; quiz 997-8. doi: 10.3928/01477447-20061101-15.