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本文引用的文献

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Relation between insufficient response to antihypertensive treatment and poor compliance with treatment: a prospective case-control study.抗高血压治疗反应不足与治疗依从性差之间的关系:一项前瞻性病例对照研究。
BMJ. 2001 Jul 21;323(7305):142-6. doi: 10.1136/bmj.323.7305.142.
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Self-reported hypertension treatment practices among primary care physicians: blood pressure thresholds, drug choices, and the role of guidelines and evidence-based medicine.基层医疗医生自我报告的高血压治疗实践:血压阈值、药物选择以及指南和循证医学的作用。
Arch Intern Med. 2000;160(15):2281-6. doi: 10.1001/archinte.160.15.2281.
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Guidelines for hypertension in the elderly--1999 revised version. Ministry of Health and Welfare of Japan.老年人高血压指南——1999年修订版。日本厚生省
Hypertens Res. 1999 Nov;22(4):231-59. doi: 10.1291/hypres.22.231.
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Compliance with antihypertensive therapy.
Clin Exp Hypertens. 1999 Jul-Aug;21(5-6):973-85. doi: 10.3109/10641969909061025.
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Compliance and medication knowledge among elderly Japanese home-care recipients.日本居家护理老年受助者的依从性与用药知识
Eur J Clin Pharmacol. 1999 Apr;55(2):145-9. doi: 10.1007/s002280050609.
6
1999 World Health Organization-International Society of Hypertension Guidelines for the Management of Hypertension. Guidelines Subcommittee.1999年世界卫生组织-国际高血压学会高血压管理指南。指南小组委员会。
J Hypertens. 1999 Feb;17(2):151-83.
7
Inadequate management of blood pressure in a hypertensive population.高血压人群中血压管理不当。
N Engl J Med. 1998 Dec 31;339(27):1957-63. doi: 10.1056/NEJM199812313392701.
8
Actual blood pressure control: are we doing things right?实际的血压控制:我们做得对吗?
J Hypertens Suppl. 1998 Jan;16(1):S45-51.
9
The sixth report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure.全国高血压防治联合委员会第六次报告。
Arch Intern Med. 1997 Nov 24;157(21):2413-46. doi: 10.1001/archinte.157.21.2413.
10
Blood-pressure control in the hypertensive population.高血压人群的血压控制
Lancet. 1997 Feb 15;349(9050):454-7. doi: 10.1016/s0140-6736(96)07099-7.

在日本老年人群中,尽管治疗的高血压患者用药依从性良好,但仍有相当一部分患者的血压未得到有效控制。

Treated hypertensives with good medication compliance are still in a state of uncontrolled blood pressure in the Japanese elderly.

机构信息

Department of Medical Science and Welfare, Institute of Community Medicine, University of Tsukuba, Tennoudai 1-1-1, 305-8575, Tsukuba-shi, Ibaraki-ken, Japan.

出版信息

Environ Health Prev Med. 2002 Nov;7(5):193-8. doi: 10.1007/BF02898004.

DOI:10.1007/BF02898004
PMID:21432277
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2723586/
Abstract

OBJECTIVES

Blood pressure (BP) is poorly controlled in many countries. Poor compliance was suggested as the main cause for poor BP control. The purpose of this study was to examine the association between compliance and the control of both casual blood pressure (BP) and 24-hr ambulatory BP in a Japanese elderly population.

METHODS

The study was a cross-sectional survey. Casual BP and 24-hr ambulatory BP were measured at home. Hypertension was defined as casual systolic BP (SBP)≧140 and/or diastolic BP (DBP)≧90 mmHg, or as treated hypertension. A compliance rate of greater than 80% by the pill count method was defined as good compliance.

RESULTS

Of the 178 treated hypertensives, 82.6% showed good compliance. Between the treated hypertensives with good compliance and those with poor compliance, no significant difference was found in either casual BP or ambulatory BP. Of the treated hypertensives with good compliance, the prevalence of achieved target ambulatory BP, i.e., daytime BP<135/85 mmHg, nighttime BP<120/75 mmHg, and 24-hr BP<125/80 mmHg, was, respectively, 35.4%, 43.5%, and 20.4%.

CONCLUSIONS

Casual BP and 24-hr ambulatory BP were poorly controlled in the community-living elderly although many of the treated hypertensives showed good compliance. It is unlikely that this inadequate control of hypertension is due to poor compliance on the part of the subjects.

摘要

目的

许多国家的血压(BP)控制不佳。较差的依从性被认为是血压控制不佳的主要原因。本研究旨在探讨日本老年人群中依从性与偶测血压(BP)和 24 小时动态血压控制之间的关系。

方法

该研究为横断面调查。在家中测量偶测血压和 24 小时动态血压。高血压定义为偶测收缩压(SBP)≧140 和/或舒张压(DBP)≧90mmHg,或治疗性高血压。以药片计数法评估的依从率大于 80%定义为良好依从性。

结果

在 178 例接受治疗的高血压患者中,82.6%表现出良好的依从性。在依从性良好和依从性差的治疗性高血压患者之间,偶测 BP 或动态 BP 无显著差异。在依从性良好的治疗性高血压患者中,达到目标动态血压的比例分别为白天血压<135/85mmHg、夜间血压<120/75mmHg 和 24 小时血压<125/80mmHg,分别为 35.4%、43.5%和 20.4%。

结论

尽管许多治疗性高血压患者表现出良好的依从性,但社区居住的老年人偶测血压和 24 小时动态血压控制不佳。高血压控制不足不太可能是由于患者依从性差所致。