Department of Hygiene, School of Medicine, Wakayama Medical University, 27 Kyubancho, 640, Wakayama, Japan.
Environ Health Prev Med. 1996 Jul;1(2):71-5. doi: 10.1007/BF02931193.
To clarify the effects of infrasound on gastric mucosal blood flow, rats were exposed to infrasound for 20 minutes. The sounds were pure tones of 8, 16 and 32 Hz, at sound levels ranging from 80 dB to 130 dB. Gastric mucosal blood flow was determined by the inhaled hydrogen gas clearance method. Norepinephrine and epinephrine concentrations in the plasma were also measured. The exposed rats showed decreased gastric mucosal blood flow with increasing sound levels of infrasound at each octave-band frequency. To significantly decrease the gastric mucosal blood flow, infrasound at 32, 16 and 8 Hz needed sound levels of 100, 110 and 130 dB, respectively. These findings suggest that, as the frequency of infrasound decreases, an increased sound level is necessary to decrease the gastric mucosal blood flow. The norepinephrine and epinephrine concentrations in the plasma were 0.65±0.47n.g/ml and 0.35±0.43 ng/ml, respectively, in the control rats, while the corresponding values were 0.91±0.87 ng/ml and 0.74±0.81 ng/ml, respectively, in the exposed rats. There were significant increases (p>0.05) in norepinephrine and epinephrine. Thus, it is probable that exposure to infrasound stimulates the sympathetic nervous system and causes a decrease in gastric mucosal blood flow.
为了阐明次声对胃黏膜血流的影响，将大鼠暴露于次声中 20 分钟。这些声音是 8、16 和 32 Hz 的纯音，声级范围为 80 dB 至 130 dB。胃黏膜血流通过吸入氢气清除法确定。还测量了血浆中的去甲肾上腺素和肾上腺素浓度。结果显示，随着各倍频带次声声级的增加，暴露大鼠的胃黏膜血流减少。要显著降低胃黏膜血流，32、16 和 8 Hz 的次声需要分别达到 100、110 和 130 dB 的声级。这些发现表明，随着次声频率的降低，需要增加声级才能降低胃黏膜血流。对照组大鼠血浆中的去甲肾上腺素和肾上腺素浓度分别为 0.65±0.47n.g/ml 和 0.35±0.43ng/ml，而暴露组大鼠的相应值分别为 0.91±0.87ng/ml 和 0.74±0.81ng/ml。去甲肾上腺素和肾上腺素均显著增加（p>0.05）。因此，次声暴露可能会刺激交感神经系统，导致胃黏膜血流减少。
