Institute of Pathology, University Hospital, Heidelberg, Germany.
Hepatology. 2011 Jun;53(6):2112-21. doi: 10.1002/hep.24313.
Over the last decade, numerous small and high-dimensional profiling analyses have been performed in human hepatocellular carcinoma (HCC), which address different levels of regulation and modulation. Because comprehensive analyses are lacking, the following review summarizes some of the general results and compares them with insights from other tumor entities. Particular attention is given to the impact of these results on future diagnostic and therapeutic approaches.
在过去的十年中,已经在人类肝细胞癌 (HCC) 中进行了许多小型和高维的分析,这些分析涉及不同层次的调控。由于缺乏全面的分析,因此本文综述了一些一般结果,并将其与来自其他肿瘤实体的见解进行了比较。特别关注这些结果对未来诊断和治疗方法的影响。