Lushchekina E A, Podreznaia E D, Lushchekin V S, Strelets V B
Zh Vyssh Nerv Deiat Im I P Pavlova. 2010 Nov-Dec;60(6):657-66.
The work represents the results of a comparative study of spectral power as well as averaged coherence in alpha, beta and gamma EEG bands in 5-to-7-year-old autistic and healthy boys in the state of rest and under cognitive load (mental calculation). The mean age of the examined children was 6 years 4 months. In both healthy and autistic children, there was a clear-cut baseline frontal-occipital gradient of the alpha activity. Performance of the cognitive task led to enhancement of spectral power in the alpha1 band and shifting its maximum to the left hemisphere, did not change the activity in the alpha2 band, and considerably increased the spectral power in the alpha3 band. In healthy children, the spectral power and average coherence of the fast rhythms increased in the central and frontal areas of the left hemisphere. The right-side dominance of the spectral power of the alpha band was revealed in autistic children both in the baseline and during cognitive task. The spectral power of the gamma band was higher in autistic children than in healthy children in the baseline. The cognitive task did not change this fast activity in autistic children.
这项研究呈现了对5至7岁自闭症男孩和健康男孩在静息状态及认知负荷（心算）下，脑电图α、β和γ频段的频谱功率以及平均相干性的比较研究结果。被检查儿童的平均年龄为6岁4个月。在健康儿童和自闭症儿童中，α活动均呈现出明显的从额叶到枕叶的基线梯度。执行认知任务导致α1频段的频谱功率增强，且其最大值向左半球转移，α2频段的活动未发生变化，而α3频段的频谱功率大幅增加。在健康儿童中，左半球中央和额叶区域的快速节律的频谱功率和平均相干性增加。在基线状态及认知任务期间，自闭症儿童的α频段频谱功率均表现为右侧优势。在基线状态下，自闭症儿童的γ频段频谱功率高于健康儿童。认知任务并未改变自闭症儿童的这种快速活动。
