Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco.
J Ovarian Res. 2011 Mar 24;4:5. doi: 10.1186/1757-2215-4-5.
Malignant transformation is a rare complication of mature cystic teratoma with squamous cell carcinoma being the most common type. We report a new case of squamous cell carcinoma in situ.
A 62 year old woman was admitted for an abdomino-pelvic mass and she underwent a left salpingo-oophorectomy. The histopathologic analysis revealed a squamous cell carcinoma in situ arising in mature cystic teratoma of the ovary. Then, she underwent a total hysterectomy, contralateral salpingo-oophorectomy and omentectomy without adjuvant treatment.
Optimal cytoreduction has been associated with a statistically significant improvement in survival for malignant transformation of mature cystic teratoma.
恶性转化是成熟囊性畸胎瘤的罕见并发症,其中以鳞状细胞癌最为常见。我们报告一例鳞状细胞癌原位病例。
一位 62 岁女性因腹部和盆腔肿块入院,接受了左侧输卵管卵巢切除术。组织病理学分析显示,卵巢成熟囊性畸胎瘤中出现了鳞状细胞癌原位。随后,她接受了全子宫切除术、对侧输卵管卵巢切除术和网膜切除术,未进行辅助治疗。
对于成熟囊性畸胎瘤的恶性转化,最佳的肿瘤细胞减灭术与统计学上生存改善相关。