Avcı Suna, Selcukbiricik Fatih, Bilici Ahmet, Ozkan Gülkan, Ozağarı Ayse Ayşim, Borlu Fatih
Division of Internal Medicine, Sisli Education and Research Hospital, 34200 Istanbul, Turkey.
Case Rep Obstet Gynecol. 2012;2012:314535. doi: 10.1155/2012/314535. Epub 2012 Dec 23.
Introduction. Malignant transformation in a mature cystic teratoma of the ovary is a rare complication. Squamous cell carcinoma is the most common transformation. We describe a new case of squamous cell carcinoma arising in a mature cystic teratoma. Case Report. A premenopausal 52-year-old female patient is diagnosed with vaginal bleeding. According to examination made on the women and the pelvic scanning, 7 cm mass is found on the right adnexa of the patient. Total abdominal hysterectomy, bilateral salpingo-oophorectomy, omentectomy, pelvic lymph node dissection, and debulking were the treatments completed on the patient. According to histopathological diagnosis, squamous cell carcinoma arising in a mature cystic teratoma is diagnosed as a reason for the mass in the right adnexa of the patient. Conclusion. The prognosis of the malign transformation of MCT depends on surgery stage; however it is extremely poor. The patient should receive chemotherapy regardless of stage. We have decided to administer second cycle carboplatin and paclitaxel treatments on the patient.
引言。卵巢成熟囊性畸胎瘤发生恶变是一种罕见的并发症。鳞状细胞癌是最常见的恶变类型。我们描述了一例起源于成熟囊性畸胎瘤的鳞状细胞癌新病例。病例报告。一名52岁绝经前女性患者被诊断为阴道出血。根据对该女性的检查及盆腔扫描，在患者右侧附件发现一个7厘米的肿块。对该患者实施了全腹子宫切除术、双侧输卵管卵巢切除术、大网膜切除术、盆腔淋巴结清扫术及肿瘤减灭术。根据组织病理学诊断，起源于成熟囊性畸胎瘤的鳞状细胞癌被诊断为患者右侧附件肿块的病因。结论。成熟囊性畸胎瘤恶变的预后取决于手术分期；然而预后极差。无论分期如何，患者均应接受化疗。我们已决定对该患者进行第二周期的卡铂和紫杉醇治疗。
