Favila-Castillo L, Jarra W, Brown K N
Division of Parasitology, National Institute for Medical Research, London, U.K.
Parasite Immunol. 1990 May;12(3):297-307. doi: 10.1111/j.1365-3024.1990.tb00956.x.
The transfer of spleen cells from CBA/Ca mice recovered from a P. c. chabaudi AS primary infection into irradiated syngeneic recipients conferred very poor protection. Neither elimination of Ly2 cells from immune spleen cells nor reinfection of the donors some days before transfer improved protection significantly. Significant protection was transferred with spleen cells from donors which had been infected 7 times prior to cell transfer. Transferred protection was reduced or eliminated by pretreatment of cells with anti-Thy-1 or anti-L3T4 monoclonal antibodies but not with anti-Ly2.
将从感染约氏疟原虫（P. c. chabaudi）AS初次感染中恢复的CBA/Ca小鼠的脾细胞转移到经照射的同基因受体中，所提供的保护作用非常差。从免疫脾细胞中去除Ly2细胞，或者在转移前几天对供体进行再次感染，均未显著改善保护作用。将来自在细胞转移前已感染7次的供体的脾细胞转移，可提供显著的保护作用。用抗Thy-1或抗L3T4单克隆抗体对细胞进行预处理可降低或消除转移的保护作用，但用抗Ly2抗体处理则不会。
