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胸腺癌伴脊柱原发性转移。

Thymic carcinoma with primary spine metastasis.

机构信息

Department of Orthopaedics, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.

出版信息

J Clin Neurosci. 2011 Jun;18(6):840-2. doi: 10.1016/j.jocn.2010.08.038. Epub 2011 Mar 23.

Abstract

Thymic carcinomas (TC) are rare tumors, representing 0.2% to 1.5% of all malignancies, with extrathoracic metastases to liver, kidney and bone occurring in 1% to 15% of patients. Although TC exhibit highly aggressive biological behavior, spinal metastasis with cord compression is rare. We describe a 57-year-old man with a 2-month history of cervicodorsal pain diagnosed with TC with primary spinal metastasis. We conclude that TC should be considered in the differential diagnosis in patients who have developed spine metastatic tumors. Early detection and appropriate surgical treatment can lead to preservation of spinal stability and neurologic improvement.

摘要

胸腺癌是一种罕见的肿瘤,占所有恶性肿瘤的 0.2%至 1.5%,1%至 15%的患者会出现肝、肾和骨的胸外转移。尽管胸腺癌具有高度侵袭性的生物学行为,但脊髓压迫性脊柱转移较为罕见。我们描述了一位 57 岁男性,2 个月前出现颈背部疼痛,被诊断为胸腺癌合并原发性脊柱转移。我们的结论是,对于出现脊柱转移瘤的患者,应考虑胸腺癌作为鉴别诊断。早期发现和适当的手术治疗可以保持脊柱稳定性和改善神经功能。

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