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恶性胸腺瘤酷似硬膜外脓肿的硬膜外转移:病例报告及文献综述

Epidural Metastasis in Malignant Thymoma Mimicking Epidural Abscess: Case Report and Literature Review.

作者信息

Kim Ji Yoon, Lee Young Seok, Kang Dong Ho, Kim Min Hye, Lee Jeong Hee, Lee Chul Hee, Park In Sung

机构信息

Department of Anesthesiology and Pain Medicine, Gyeongsang National University School of Medicine, Jinju, Korea.

Department of Neurosurgery, Gyeongsang National University School of Medicine, Jinju, Korea.

出版信息

Korean J Spine. 2017 Dec;14(4):162-165. doi: 10.14245/kjs.2017.14.4.162. Epub 2017 Dec 31.

Abstract

Thymoma and thymic carcinoma are rare epithelial tumors that originate from the thymus gland. Extrathoracic metastases occur in the liver, kidney, and bone in 1% to 15% of patients. Although thymoma and thymic carcinoma exhibit highly aggressive biological behavior, spinal metastasis is rare. We describe a 78-year-old man with left wrist and grasp weakness that occurred 7 days before admission. The patient underwent thymoma surgery 7 years ago and was cured. Magnetic resonance images showed a rim-enhanced mass in the C6-7-T1 epidural space. C6-7-T1 laminectomy was performed and the mass was removed. Histological examination was performed and patient was diagnosed with metastatic thymoma. The previous reported case occurred with involvement of the vertebral body or posterior element, but our case was mostly rim-enhanced and appeared as an abscess and intradural extramedullary tumor.

摘要

胸腺瘤和胸腺癌是起源于胸腺的罕见上皮性肿瘤。1%至15%的患者会出现肝、肾和骨的胸外转移。尽管胸腺瘤和胸腺癌表现出高度侵袭性的生物学行为,但脊柱转移却很罕见。我们描述了一名78岁男性,入院前7天出现左手腕及抓握无力。该患者7年前接受了胸腺瘤手术且已治愈。磁共振成像显示C6 - 7 - T1硬膜外间隙有环形强化肿块。进行了C6 - 7 - T1椎板切除术并切除了肿块。进行了组织学检查,患者被诊断为转移性胸腺瘤。先前报道的病例累及椎体或后部结构,但我们的病例大多为环形强化,表现为脓肿和硬脊膜外髓外肿瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a60f/5769940/e011686340d3/kjs-14-4-162f1.jpg

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