Gauchan Eva, Sharma Prakash, Ghartimagar Dilasma, Ghosh Arnab
Department of Pediatrics, Manipal College of Medical Sciences, Pokhara, Nepal.
Manipal College of Medical Sciences, Manipal Teaching Hospital, Fulbari, Pokhara, 33701, Nepal.
J Med Case Rep. 2017 Aug 29;11(1):239. doi: 10.1186/s13256-017-1397-x.
Ganglioneuroblastoma is a tumor of peripheral neuroblastic tissue which occurs predominantly in the pediatric age group; it is a rare occurrence in the newborn period with only one case reported at birth to date.
We report the case of a newborn male baby of Brahmin ethnicity from Nepal who presented with respiratory distress and blueberry muffin skin lesions after birth. A computed tomography scan showed a mass lesion in the posterior mediastinum, which was diagnosed as ganglioneuroblastoma on fine-needle aspiration cytology. He also had metastases to multiple sites including heart, lungs, skin and brain.
Ganglioneuroblastoma is a rare tumor in newborns. Any newborn presenting with respiratory distress associated with blueberry muffin skin lesions should be evaluated for neuroblastic tumor.
神经节神经母细胞瘤是一种主要发生于儿童年龄组的外周神经母细胞组织肿瘤；在新生儿期罕见，迄今为止仅有1例出生时即被报道。
我们报告1例来自尼泊尔的婆罗门族新生儿男婴，出生后出现呼吸窘迫和蓝莓松饼样皮肤损害。计算机断层扫描显示后纵隔有一肿块病变，细针穿刺细胞学检查诊断为神经节神经母细胞瘤。他还出现了包括心脏、肺、皮肤和脑在内的多部位转移。
神经节神经母细胞瘤在新生儿中是一种罕见肿瘤。任何出现与蓝莓松饼样皮肤损害相关的呼吸窘迫的新生儿都应接受神经母细胞瘤评估。
