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一种行为测量方法,用于评估暂时性阈移所涉及的耳蜗变化。

A behavioral measure of the cochlear changes underlying temporary threshold shifts.

机构信息

Audiology Department, Sunderland Royal Hospital, UK.

出版信息

Hear Res. 2011 Jul;277(1-2):78-87. doi: 10.1016/j.heares.2011.03.009. Epub 2011 Mar 23.

DOI:10.1016/j.heares.2011.03.009
PMID:21439366
Abstract

It is well documented that exposure to recreational noise may result in a temporary threshold shift (TTS) due to cochlear dysfunction. A forward-masking paradigm was used to estimate the relative contribution of inner hair cell (IHC) and outer hair cell (OHC) dysfunction to TTS. Eighteen normal-hearing adults completed a test battery before, immediately after, and one week after attending a loud music venue. Personal dosimeters recorded mean equivalent exposure levels of 99.0 dB A. Shortly after exposure, there was an average TTS of 10.8 dB at 4 kHz, and an average reduction in the estimated gain provided by the OHCs of 11.5 dB. Gain reduction correlated significantly with TTS. The results suggest that OHC dysfunction can account almost entirely for the raised thresholds. For the test battery conducted a week after exposure, all measures showed recovery to pre-exposure values.

摘要

有充分的文献记载表明,由于耳蜗功能障碍,接触娱乐性噪声可能会导致暂时阈移(TTS)。使用前掩蔽范式来估计内毛细胞(IHC)和外毛细胞(OHC)功能障碍对 TTS 的相对贡献。18 名听力正常的成年人在参加喧闹的音乐场所之前、之后立即和一周后完成了一组测试。个人剂量计记录的平均等效暴露水平为 99.0 dB A。暴露后不久,4 kHz 时的平均 TTS 为 10.8 dB,而 OHC 提供的估计增益平均降低了 11.5 dB。增益降低与 TTS 显著相关。结果表明,OHC 功能障碍几乎可以完全解释阈值升高的原因。对于暴露后一周进行的测试,所有指标均显示恢复到暴露前的值。

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