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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

el Hachimi Z, Tijane M, Boissonnet G, Benjouad A, Desmadril M, Yon J M

Laboratoire de Biochimie, Faculté des Sciences, Rabat, Morocco.

Comp Biochem Physiol B. 1990;96(3):457-9. doi: 10.1016/0305-0491(90)90039-v.

The glycolytic flow in the skeletal muscle was considerably depressed during hibernation of Jaculus orientalis. 2. Although the ATP content was not modified, the ATP/AMP ratio was twice as large than under homeothermic conditions. 3. Furthermore, the hexose phosphates were markedly depressed. 4. The total activities of the key enzymes, hexokinase, phosphofructokinase and pyruvate kinase, which are regulated through the adenylates, decreased. 5. Under in vivo conditions, taking into account the small amount of fructose-6-phosphate and the ATP/AMP ratio, it is likely that phosphofructokinase was totally inhibited, explaining the undetectable amount of fructose 1.6 bisphosphate.

东方沙鼠冬眠期间，其骨骼肌中的糖酵解通量显著降低。2. 尽管ATP含量未发生改变，但ATP/AMP比值比在恒温条件下高出一倍。3. 此外, 己糖磷酸显著降低。4. 通过腺苷酸调节的关键酶，己糖激酶、磷酸果糖激酶和丙酮酸激酶的总活性降低。5. 在体内条件下，考虑到6-磷酸果糖含量少以及ATP/AMP比值，磷酸果糖激酶很可能被完全抑制，这就解释了无法检测到1,6-二磷酸果糖的原因。

el Hachimi Z, Tijane M, Boissonnet G, Benjouad A, Desmadril M, Yon J M

Laboratoire de Biochimie, Faculté des Sciences, Rabat, Morocco.

Comp Biochem Physiol B. 1990;96(3):457-9. doi: 10.1016/0305-0491(90)90039-v.

The glycolytic flow in the skeletal muscle was considerably depressed during hibernation of Jaculus orientalis. 2. Although the ATP content was not modified, the ATP/AMP ratio was twice as large than under homeothermic conditions. 3. Furthermore, the hexose phosphates were markedly depressed. 4. The total activities of the key enzymes, hexokinase, phosphofructokinase and pyruvate kinase, which are regulated through the adenylates, decreased. 5. Under in vivo conditions, taking into account the small amount of fructose-6-phosphate and the ATP/AMP ratio, it is likely that phosphofructokinase was totally inhibited, explaining the undetectable amount of fructose 1.6 bisphosphate.

东方沙鼠冬眠期间，其骨骼肌中的糖酵解通量显著降低。2. 尽管ATP含量未发生改变，但ATP/AMP比值比在恒温条件下高出一倍。3. 此外, 己糖磷酸显著降低。4. 通过腺苷酸调节的关键酶，己糖激酶、磷酸果糖激酶和丙酮酸激酶的总活性降低。5. 在体内条件下，考虑到6-磷酸果糖含量少以及ATP/AMP比值，磷酸果糖激酶很可能被完全抑制，这就解释了无法检测到1,6-二磷酸果糖的原因。