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多发复发性恶性孤立性纤维瘤:24 年的长期随访。

Multiple recurrent malignant solitary fibrous tumors: long-term follow-up of 24 years.

机构信息

Department of Thoracic and Cardiovascular Surgery, Keimyung University School of Medicine, Daegu, South Korea.

出版信息

Ann Thorac Surg. 2011 Apr;91(4):1285-8. doi: 10.1016/j.athoracsur.2010.08.074.

DOI:10.1016/j.athoracsur.2010.08.074
PMID:21440167
Abstract

Solitary fibrous tumor (SFT) of the pleura is a rare, generally benign, neoplasm that accounts for less than 5% of all pleural tumors. However, 10% to 30% of SFTs display aggressive behavior with local recurrence, malignant transformation, and distant metastasis. We report a case of multiple recurrent SFTs of the thorax in a 77-year-old Korean woman. During a 24-year period, she underwent six surgical resections for six recurrent SFTs. The tumor eventually underwent morphologically malignant transformation. This unique case highlights the necessity of long-term follow-up in cases of SFT because of the potentially malignant biological behavior of this type of tumor.

摘要

胸膜孤立性纤维瘤(SFT)是一种罕见的、通常为良性的肿瘤,占所有胸膜肿瘤的比例不到 5%。然而,10%至 30%的 SFT 具有侵袭性行为,表现为局部复发、恶性转化和远处转移。我们报告了一例 77 岁韩国女性的多发复发性胸腔 SFT。在 24 年期间,她因 6 个复发性 SFT 接受了 6 次手术切除。肿瘤最终发生了形态学恶性转化。这个独特的病例强调了对 SFT 进行长期随访的必要性,因为这种类型的肿瘤具有潜在的恶性生物学行为。

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