Nagel G A, Nagel-Studer E, Seiler W, Hofer H O
Int J Cancer. 1978 Dec;22(6):675-8. doi: 10.1002/ijc.2910220606.
In one family four out of five siblings were affected with malignant lymphoma and HD has been diagnosed in two other relatives. HLA-haplotypes were identical for the three diseased siblings who were so studied, whereas for the unaffected one they were different.
在一个家庭中,五名兄弟姐妹中有四人患恶性淋巴瘤,另外两名亲属被诊断患有霍奇金病。对接受研究的三名患病兄弟姐妹而言,其人类白细胞抗原单倍型是相同的,而未患病的那名兄弟姐妹的单倍型则不同。