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五名兄弟姐妹中有四人患恶性淋巴瘤。

Malignant lymphoma in four of five siblings.

作者信息

Nagel G A, Nagel-Studer E, Seiler W, Hofer H O

出版信息

Int J Cancer. 1978 Dec;22(6):675-8. doi: 10.1002/ijc.2910220606.

DOI:10.1002/ijc.2910220606
PMID:214406
Abstract

In one family four out of five siblings were affected with malignant lymphoma and HD has been diagnosed in two other relatives. HLA-haplotypes were identical for the three diseased siblings who were so studied, whereas for the unaffected one they were different.

摘要

在一个家庭中,五名兄弟姐妹中有四人患恶性淋巴瘤,另外两名亲属被诊断患有霍奇金病。对接受研究的三名患病兄弟姐妹而言,其人类白细胞抗原单倍型是相同的,而未患病的那名兄弟姐妹的单倍型则不同。

相似文献

1
Malignant lymphoma in four of five siblings.五名兄弟姐妹中有四人患恶性淋巴瘤。
Int J Cancer. 1978 Dec;22(6):675-8. doi: 10.1002/ijc.2910220606.
2
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Epstein-Barr virus-associated familial Hodgkin lymphoma: paediatric onset in three of five siblings.爱泼斯坦-巴尔病毒相关的家族性霍奇金淋巴瘤:五名兄弟姐妹中有三名儿童期发病
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Discordance of Epstein-Barr Virus (EBV) specific humoral and cellular immunity in patients with malignant lymphomas: elevated antibody titres and lowered in vitro lymphocyte reactivity.恶性淋巴瘤患者中爱泼斯坦-巴尔病毒(EBV)特异性体液免疫和细胞免疫的不一致性:抗体滴度升高和体外淋巴细胞反应性降低。
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Non-Hodgkin malignant lymphomas and Hodgkin's disease in first-degree relatives. Evidence for a mutual genetic predisposition?一级亲属中的非霍奇金恶性淋巴瘤和霍奇金病。存在共同遗传易感性的证据?
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1
Pseudoautosomal linkage of Hodgkin disease.霍奇金病的拟常染色体连锁
Am J Hum Genet. 1999 Nov;65(5):1413-22. doi: 10.1086/302608.