Department of Rheumatology, El Ayachi hospital, University Hospital of Rabat-Sale, Sale, Morocco.
Joint Bone Spine. 2011 Dec;78(6):584-6. doi: 10.1016/j.jbspin.2011.02.001. Epub 2011 Mar 26.
We aimed to estimate the prevalence of overweight among Moroccan children and adolescents with juvenile idiopathic arthritis (JIA).
Fifty-eight patients with JIA according to the International League of Association of Rheumatology (ILAR) criteria were included consecutively in this study. The median age of patients was 11±3.3years (range 2-16). Overweight and obesity were defined by using the Body Mass Index (matched on age and sex and in reference to the French curves. Following data were collected: age, gender, age at onset, disease duration, subtype of JIA, functional disability (determined using the Moroccan version of Childhood Health Assessment Questionnaire [CHAQ]), disease activity (assessed using a 0-10 visual analogical scale, the number of tender and swollen joints and the erythrocyte sedimentation rate); medical treatment and socioeconomic status of patients.
Twenty-four patients (41.4%) were overweight, 13 (22.4%) were obese and 21(36.2%) have normal. Patients with normal weight, obese and overweight represented successively 16.7%, 33.3% and 50% of systemic forms, 33.3%, 8.3% and 58.3% of seronegative polyarticular forms, 40%, 40% and 20% of seropositive polyarticular forms, 36.4%, 27.3% and 36.4% of persistent oligoarticular forms, 75%, 25% and 0% of extensive oligoarticular forms and 57.1%, 0% and 42.9% of forms with arthritis and enthesitis. In our data, there was no psoriatic arthritis. Overweight and obesity were more prevalent in older patients (P=0.01), with significant functional impairment (P=0.04) and with active disease (increased VAS) (P=0.005). There were no relationships with the subtype of JIA or with corticosteroid treatment (P=0.451).
Approximatively more than 60% of our patients were overweight. Severe functional limitation and active disease are the most correlated parameters with overweight. Better management of the activity and functional status of the disease seems to be of interest to prevent overweight in children with JIA. More studies with a larger number of patients seem to be necessary in order to confirm our results.
我们旨在评估摩洛哥青少年特发性关节炎（JIA）患儿超重的患病率。
本研究连续纳入 58 例符合国际风湿病联盟（ILAR）标准的 JIA 患者。患者的中位年龄为 11±3.3 岁（范围 2-16 岁）。超重和肥胖采用身体质量指数（BMI）定义（按年龄和性别匹配，并参照法国曲线）。收集以下数据：年龄、性别、发病年龄、疾病持续时间、JIA 亚型、功能障碍（使用摩洛哥版儿童健康评估问卷[CHAQ]确定）、疾病活动度（使用 0-10 视觉模拟评分、压痛和肿胀关节数和红细胞沉降率评估）；患者的医疗和社会经济状况。
24 例（41.4%）患者超重，13 例（22.4%）肥胖，21 例（36.2%）体重正常。体重正常、肥胖和超重的患者依次为全身型占 16.7%、33.3%和 50%，血清阴性多关节炎型占 33.3%、8.3%和 58.3%，血清阳性多关节炎型占 40%、40%和 20%，持续性少关节炎型占 36.4%、27.3%和 36.4%，广泛少关节炎型占 75%、25%和 0%，关节炎和附着点病型占 57.1%、0%和 42.9%。在我们的数据中，没有银屑病关节炎。超重和肥胖更常见于年龄较大的患者（P=0.01），且存在显著的功能障碍（P=0.04）和疾病活动度增加（VAS）（P=0.005）。与 JIA 亚型或皮质类固醇治疗无相关性（P=0.451）。
我们的患者中约有 60%以上超重。严重的功能受限和疾病活动度是与超重最相关的参数。更好地管理疾病的活动和功能状态似乎有助于预防 JIA 患儿超重。为了证实我们的结果，似乎需要进行更多的研究，纳入更多的患者。
