Pouchot Jacques, Larbre Jean-Paul, Lemelle Irène, Sommelet Danièle, Grouteau Eric, David Louis, Duquesne Agnès, Deslandre Chantal Job, Koné Paut Isabelle, Pillet Pascal, Goumy Laurence, Barbier Catherine, Guyot Marie-Hélène, Mazingue Françoise, Laloum Sylvie Gandon, Fischbac Michel, Quartier Pierre, Guyot Claude, Jean Sylvie, Legall Edouard, Plouvier Emmanuel, Bost Michel, de Lumley Lionel, Brégeon Christian, Guillemin Francis, Coste Joël, Prieur Anne-Marie
Internal Medicine Department, Médecine Interne, Hĵpital Louis Mourier, 178, rue des Renoullers, Colombes, France.
Joint Bone Spine. 2002 Oct;69(5):468-81. doi: 10.1016/s1297-319x(02)00432-3.
To translate, cross-culturally adapt, and validate the functional disability tool Childhood Health Assessment Questionnaire (CHAQ), a variant of the Health Assessment Questionnaire (HAQ), in children with juvenile idiopathic arthritis (JIA).
The disability index is the mean of the scores on the eight domains of the CHAQ and can range from 0 (no disability) to 3 (maximum disability). The CHAQ was first translated into French and adapted, then validated in a multicenter cross-sectional study in 306 children with JIA (systemic onset, 23%; polyarticular onset, 22%; extended oligoarticular subtype, 25%; and persistent oligoarticular subtype, 30%).
Overall CHAQ scores discriminated between the four JIA subtypes (systemic: 1.1 +/- 0.9; polyarticular: 0.8 +/- 0.7, extended oligoarticular 0.8 +/- 0.7, and persistent oligoarticular: 0.4 +/- 0.5 [P < 0.0001]). Reproducibility evaluated by test-retest at a 7-day interval was excellent (intraclass coefficient, 0.91), as was agreement between the Parent's and Children's versions of the questionnaire (intraclass coefficient, 0.89). Significant correlations were found between the overall CHAO score and variables reflecting disease severity (joint counts, physician's and parent's global assessments, and erythrocyte sedimentation rate), indicating excellent convergent validity of the tool.
The French version of the CHAQ displays good psychometric characteristics, although its sensitivity to change remains to be established. The French version of the CHAO should prove useful in international studies and can be expected to be helpful for monitoring individual patients with JIA.
对功能残疾工具儿童健康评估问卷（CHAQ）进行翻译、跨文化调适及验证，CHAQ是健康评估问卷（HAQ）的一个变体，用于幼年特发性关节炎（JIA）患儿。
残疾指数是CHAQ八个领域得分的平均值，范围从0（无残疾）到3（最大残疾）。CHAQ首先被翻译成法语并进行调适，然后在一项多中心横断面研究中对306例JIA患儿（全身型，23%；多关节型，22%；扩展性少关节型，25%；持续性少关节型，30%）进行验证。
总体CHAQ得分在四种JIA亚型之间存在差异（全身型：1.1±0.9；多关节型：0.8±0.7，扩展性少关节型0.8±0.7，持续性少关节型：0.4±0.5 [P<0.0001]）。通过间隔7天的重测评估的可重复性极佳（组内相关系数，0.91），问卷家长版和儿童版之间的一致性也很好（组内相关系数，0.89）。在总体CHAQ得分与反映疾病严重程度的变量（关节计数、医生和家长的整体评估以及红细胞沉降率）之间发现了显著相关性，表明该工具具有良好的聚合效度。
CHAQ法语版显示出良好的心理测量学特征，尽管其对变化的敏感性仍有待确定。CHAQ法语版在国际研究中应会有用，并且有望有助于监测JIA个体患者。
