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[自闭症谱系障碍的共病——研究现状与未来展望]

[Comorbidities with autism spectrum disorders - present state of research and future outlook].

作者信息

Sinzig Judith, Lehmkuhl Gerd

机构信息

Abteilung für Kinder- und Jugendpsychiatrie und Psychotherapie, LVR-Klinik Bonn.

出版信息

Z Kinder Jugendpsychiatr Psychother. 2011 Mar;39(2):91-8; quiz 99. doi: 10.1024/1422-4917/a000095.

Abstract

Numerous somatic and psychopathological disorders occur parallel with autism spectrum disorders. It is presently being discussed whether other co-occurring psychopathological symptoms should constitute a categorical comorbid disorder on their own right and be diagnosed as such; or whether they should be understood as part of the autistic disorder itself. Based on the situation with attention deficit/hyperactivity disorder (ADHD), the current state of research and our own research results are used as examples to demonstrate which prerequisites must be fulfilled for a comorbid disorder. Furthermore, based on neurobiological findings from the areas of molecular biology, neuropsychology, and imaging we show which requirements emerge for the aetiology, early detection, pharmacological and psychotherapeutic treatment, course of illness, and the categorical classification approach.

摘要

许多躯体和精神病理学障碍与自闭症谱系障碍同时出现。目前正在讨论其他同时出现的精神病理学症状是否应凭自身构成一种分类共病障碍并如此诊断;或者它们是否应被理解为自闭症障碍本身的一部分。基于注意力缺陷多动障碍(ADHD)的情况,以当前的研究现状和我们自己的研究结果为例,来说明共病障碍必须满足哪些前提条件。此外,基于分子生物学、神经心理学和影像学领域的神经生物学发现,我们展示了病因学、早期检测、药物和心理治疗、病程以及分类方法方面出现了哪些要求。

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