Fedorov V V, Kovalenko A D, Ivanov V P
Sov Med. 1990(6):3-7.
Profound disturbances of the immunologic homeostasis system are a characteristic feature of cardiac muscle inflammations. Depressed rosette formation in patients with non-coronarogenic diseases of the myocardium is associated with impaired maturation of immunocompetent cells and with severe inhibition of suppressor function, this resulting in perversed proliferative response to phytohemagglutinin. In patients with dystrophic and functional diseases of the cardiac muscle the activity of short-lived suppressors is unchanged; therefore examination of this parameter may be helpful in the differential diagnosis between inflammatory and dystrophic diseases of the myocardium.
免疫稳态系统的严重紊乱是心肌炎症的一个特征。非冠状动脉性心肌疾病患者玫瑰花结形成降低与免疫活性细胞成熟受损及抑制功能严重受抑有关,这导致对植物血凝素的异常增殖反应。在心肌营养不良和功能性疾病患者中,短命抑制细胞的活性未改变;因此,检查这一参数可能有助于心肌炎症性疾病和营养不良性疾病的鉴别诊断。