Department of Radiation Oncology, Southern Tohoku Proton Therapy Center, 7-172 Yatsuyamada, Koriyama, Fukushima 963-8052, Japan.
Oral Oncol. 2011 May;47(5):387-90. doi: 10.1016/j.oraloncology.2011.03.010. Epub 2011 Mar 27.
To determine whether anticancer drugs delivered via arterial infusion can permeate entire tumors using a new MRI flow check method. We infused 20 ml of contrast medium (2 ml of Gd-GDPA plus 18 ml of normal saline) over a period of 10 min using a continuous injection pump, then immediately performed MRI using a 1.5 T unit. Images were obtained in 5-mm-thick continuous sections in two or three planes (axial, coronal, and sagittal) depending on the extent of the tumor, and enhanced fast gradient echo 3 D (EFGRE3D) images with a special inversion at lipids were photographed using a neurovascular array coil. The new MRI flow check method delineated an area of tongue cancer perfused with drugs more accurately than conventional methods.The MRI flow check method provides accurate information about areas of arterial infusion.
为了确定通过动脉输注的抗癌药物是否可以使用新的 MRI 流量检查方法渗透整个肿瘤。我们使用连续注射泵在 10 分钟内输注 20 毫升造影剂（2 毫升 Gd-GDPA 和 18 毫升生理盐水），然后立即使用 1.5 T 装置进行 MRI。根据肿瘤的范围，在两个或三个平面（轴位、冠状位和矢状位）获得 5 毫米厚的连续切片图像，并使用神经血管阵列线圈拍摄具有特殊反转的增强快速梯度回波 3D（EFGRE3D）图像。新的 MRI 流量检查方法比传统方法更准确地描绘了用药物灌注的舌癌区域。MRI 流量检查方法提供了有关动脉输注区域的准确信息。
