Wang Vision Institute, Nashville, TN, USA.
Cornea. 2011 Sep;30(9):968-71. doi: 10.1097/ICO.0b013e3182031ca0.
: To describe 4 cases of corneal melt encountered after insertion of intrastromal corneal ring segments (ICRS) for ectasia, propose a theory as to the etiology of the melt, and review relevant literature.
: Retrospective observational case series. Eyes with corneal melt after ICRS implantation were identified and the charts were reviewed. Relevant literature was reviewed to establish the overall incidence of corneal melt after ICRS and potential contributing factors.
: Each of our 4 cases of corneal melt occurred in an eye with a corneal incision overlying the ICRS. Case 1 occurred in an eye with pellucid marginal degeneration in which the ICRS incision overlaid the segment. Case 2 occurred in an eye after radial keratotomy that underwent ICRS to address refractive instability. Corneal melt developed around a gaping radial keratotomy (RK) incision. Case 3 occurred in an eye after radial keratotomy and subsequent hyperopic laser in situ keratomileusis that developed ectasia for which an ICRS was inserted. Corneal melt developed in association with an RK incision overlying the ICRS in the area of a peripheral corneal ulcer. Case 4 occurred in an eye after radial keratotomy with an unstable cornea that underwent ICRS implantation for improved stability. The ring segment extruded through an overlying RK incision and corneal melt developed. The literature on ICRS implantation for keratoconus and ectasia was reviewed. Of 1835 eyes after ICRS implantation for keratoconus or ectasia, there were 12 reported cases of corneal melt (0.7%), a majority (7% or 58%) were associated with overlying incision.
: Corneal melt is a rare complication of ICRS. We conclude that wound gape over ICRS contributes to the development of melt. Strategies can be employed to reduce the incidence of this rare but important complications of ICRS.
描述 4 例因扩张症而植入间质角膜环段(ICRS)后发生的角膜溶解病例,提出一种关于溶解病因的理论,并回顾相关文献。
回顾性观察性病例系列研究。确定植入 ICRS 后发生角膜溶解的眼睛,并回顾图表。回顾相关文献,以确定 ICRS 后角膜溶解的总体发生率和潜在的促成因素。
我们 4 例角膜溶解病例中的每一例均发生在 ICRS 上方角膜切口的眼睛。病例 1 发生在角膜边缘变性的眼睛中,ICRS 切口覆盖了该段。病例 2 发生在接受 ICRS 治疗屈光不稳定的放射状角膜切开术后的眼睛。角膜溶解发生在一个大的放射状角膜切开术(RK)切口周围。病例 3 发生在接受放射状角膜切开术和随后远视激光原位角膜磨镶术的眼睛中,该手术因扩张而插入 ICRS。角膜溶解与 ICRS 上方的 RK 切口相关,位于周边角膜溃疡的区域。病例 4 发生在角膜不稳定的眼睛中,该眼睛在接受 ICRS 植入以提高稳定性后发生了 RK 切口。环段通过上方的 RK 切口突出,导致角膜溶解。对 ICRS 植入治疗圆锥角膜和扩张症的文献进行了回顾。在 1835 例因圆锥角膜或扩张症而接受 ICRS 植入的眼中,有 12 例报告了角膜溶解(0.7%),其中大多数(7%或 58%)与上方切口有关。
角膜溶解是 ICRS 的罕见并发症。我们得出结论,ICRS 上方的伤口张开有助于溶解的发展。可以采用策略来降低这种罕见但重要的 ICRS 并发症的发生率。