Nuzzi Raffaele, Tripoli Flavia, Rossi Alessandro, Ghilardi Andrea
Department of Ophthalmology, University of Turin, Turin, Italy.
Front Med (Lausanne). 2022 Mar 11;9:853702. doi: 10.3389/fmed.2022.853702. eCollection 2022.
Keratoconus is a non-inflammatory and degenerative corneal ectasia that determinate progressive steepening of paracentral cornea with development of irregular astigmatism and visual function deterioration. According to the stage of the pathology, different methods of correction can be used: rigid contact lenses may be used to alter corneal shape and partially correct astigmatism, corneal collagen cross-linking (CXL) and intrastromal corneal ring segment (ICRS) implantation can reinforce corneal stroma to slow disease progression. Late-stage treatment comprehend anterior lamellar keratoplasty or penetrating keratoplasty. We evaluated a 31-year-old patient who was subjected to bilateral ICRS implantation combined with CXL due to keratoconus. This led, after 9 months, to ring extrusion in his left eye, corneal thinning and microperforation into the aqueous chamber with residual irregular astigmatism of 4.50 D. cyl. 10°. The patient underwent ICRS explantation and PKP during the same surgical session. After 15 months of follow-up, the BCVA was 0.2 LogMAR with a residual astigmatism of 6.3 dpt.
圆锥角膜是一种非炎症性退行性角膜扩张症,其特征是角膜旁中央区域逐渐陡峭,伴有不规则散光的发展和视功能恶化。根据病理阶段,可以采用不同的矫正方法:硬性接触镜可用于改变角膜形状并部分矫正散光,角膜胶原交联(CXL)和角膜基质内环形植片(ICRS)植入可增强角膜基质以减缓疾病进展。晚期治疗包括前板层角膜移植术或穿透性角膜移植术。我们评估了一名31岁因圆锥角膜接受双侧ICRS植入联合CXL治疗的患者。9个月后,其左眼出现环形植片脱出、角膜变薄并向房水腔微小穿孔,残留4.50 D柱镜、10°的不规则散光。患者在同一次手术中接受了ICRS取出术和穿透性角膜移植术。随访15个月后,最佳矫正视力为0.2 LogMAR,残留散光为6.3 dpt。