Department of Psychiatry, Faculty of Medicine and Dentistry, Palacky University Olomouc, I. P. Pavlova 6, Olomouc, 775 20, Czech Republic.
Psychiatr Danub. 2011 Mar;23(1):21-6.
In the past, the first goal of bipolar disorder treatment was the reduction of symptoms of mania or depression, rather than the recovery of social functioning. Recently, as a result of an increased emphasis on patient needs, the concept of quality of life (QoL) has been brought into the treatment of physical illnesses.
The purpose of the present study was to examine QoL data in patients with bipolar disorder in clinical remission and to determine the extent of the effects of demographic and clinical data on QoL in these patients. The second aim was to compare the QoL data of these patients to that of patients with schizophrenia in clinical remission and to that of healthy controls. Data were obtained using a QoL questionnaire (Quality of Life Enjoyment and Satisfaction Questionnaire, or Q-LES-Q) for 41 bipolar patients in clinical remission. The data were then compared with the data of 40 schizophrenic patients in clinical remission and with 40 healthy controls.
There were higher mean scores in most Q-LES-Q summary scales in the bipolar patients than in the schizophrenic patients. There were higher mean scores in the bipolar patients in some summary scales than in the healthy controls.
Our results suggest the same or higher subjective QoL in bipolar patients in clinical remission in comparison with healthy controls and higher subjective QoL in bipolar patients in clinical remission than in schizophrenic patients in clinical remission.
过去，双相情感障碍治疗的首要目标是减轻躁狂或抑郁症状，而不是恢复社会功能。最近，由于更加关注患者的需求，生活质量（QoL）的概念已被纳入到躯体疾病的治疗中。
本研究旨在考察处于临床缓解期的双相情感障碍患者的 QoL 数据，并确定人口统计学和临床数据对这些患者 QoL 的影响程度。第二个目的是将这些患者的 QoL 数据与处于临床缓解期的精神分裂症患者以及健康对照组进行比较。使用生活质量问卷（生活质量享受和满意度问卷，或 Q-LES-Q）获得 41 例处于临床缓解期的双相情感障碍患者的数据。然后将这些数据与 40 例处于临床缓解期的精神分裂症患者和 40 例健康对照组的数据进行比较。
大多数 Q-LES-Q 综合量表的双相情感障碍患者的平均得分均高于精神分裂症患者。在某些综合量表中，双相情感障碍患者的平均得分高于健康对照组。
我们的结果表明，处于临床缓解期的双相情感障碍患者的主观 QoL 与健康对照组相同或更高，且处于临床缓解期的双相情感障碍患者的主观 QoL 高于处于临床缓解期的精神分裂症患者。
