Baker S R
Dept. of Otolaryngology-Head and Neck Surgery, U. of Michigan Hospitals, Ann Arbor.
Oncology (Williston Park). 1990 Sep;4(9):107-20; discussion 122-4.
Carcinoma of the lip is the most common cancer of the oral cavity, occurring most frequently on the lower lip of elderly males. Less advanced neoplasms may be treated equally successfully by surgery or irradiation, and results are cosmetically acceptable by both methods. Reconstruction of the lip following surgical ablation of tumor usually consists of primary repair. Larger defects require flaps from the opposite lip, adjacent cheek, or more distant tissue. Although prophylactic neck dissection is usually not indicated, the presence of neck metastases from carcinoma of the lip is best managed by neck dissection followed by postoperative radiotherapy. The prognosis for curing lip cancer is dependent upon the size of the primary tumor and whether cervical metastasis has occurred. The overall five-year cure rate of lip cancer approximates 80%. The cure rate of patients with neck metastases is approximately 50%.
唇癌是口腔最常见的癌症,最常发生于老年男性的下唇。不太晚期的肿瘤通过手术或放疗治疗均可取得同样成功的效果,两种方法的美容效果均可接受。肿瘤手术切除后唇部的重建通常采用一期修复。较大的缺损需要取自对侧唇部、邻近面颊或更远部位组织的皮瓣。虽然通常不主张进行预防性颈部清扫,但唇癌出现颈部转移时,最好的处理方法是行颈部清扫术,术后辅以放疗。唇癌的治愈预后取决于原发肿瘤的大小以及是否发生了颈部转移。唇癌的总体五年治愈率约为80%。有颈部转移的患者治愈率约为50%。